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J. pediatr. (Rio J.) ; 82(2): 157-160, Mar.-Apr. 2006. ilus, graf
Artículo en Inglés | LILACS | ID: lil-428497

RESUMEN

OBJECTIVE: To report a pediatric case of central pontine and extrapontine myelinolysis, a rare neurological disease often associated with rapid correction of hyponatremia.DESCRIPTION: A 15 year-old female adolescent developed locked-in syndrome during severe hyponatremia. Brain magnetic resonance imaging was consistent with the diagnosis of central pontine and extrapontine myelinolysis.COMMENTS: Serum sodium correction should proceed slowly and cautiously, based upon a careful calculation of sodium deficit, in order to minimize metabolic stress and avoid the occurrence of this dreadful complication, which has a tragic outcome in most cases. There is no scientifically proved effective treatment for myelinolysis, and severe cases usually have a dismal prognosis.


Asunto(s)
Humanos , Femenino , Adolescente , Hiponatremia/diagnóstico , Mielinólisis Pontino Central/diagnóstico , Cerebro/patología , Resultado Fatal , Hiponatremia/etiología , Hiponatremia/terapia , Imagen por Resonancia Magnética , Mielinólisis Pontino Central/etiología , Sodio/sangre
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