RESUMEN
Haemophilus influenzae B(Hib) is often associated with serious systemic infections in children under 5 years of age. Since 1993, it is the most frequent agent isolated in meningoencephalitis. All the strains isolated in the country have been characterized in the National Reference Laboratory at the "Pedro KourÝ" Tropical Medicine Institute. Results revealed that 97 of strains isolated from bacterial meningoencephalitis in Cuba during the period 1993-1995 corresponded to serotype B, 0.6 to serotype A and 2.4 not belong to any serotype. The classification of serotype B-strains into biotypes proved that 76 was biotype I and 21 biotype II, 8 to biotype III and 1.2 was biotype V. This study found the following resistance to ampicillin 40, to chloranphenicol 43.3, sulpha metoxazol 36, trimetroprim 37.3 and tetracycline 31.