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Rev. Soc. Bras. Med. Trop ; 53: e20190583, 2020. tab, graf
Artículo en Inglés | SES-SP, ColecionaSUS, LILACS | ID: biblio-1136797

RESUMEN

Abstract INTRODUCTION: We performed an epidemiological surveillance of the Chikungunya (CHIKV) lineages in Bahia after the 2014 East/Central/South African (ECSA) genotype outbreak. METHODS: Reverse-transcription polymerase chain reaction (RT-PCR), viral isolation, and phylogenetic analyses were conducted on serum samples from 605 patients with CHIKV-like symptoms during 2014-2018. RESULTS: Of the 605 samples, 167 were CHIKV-positive. Viral isolation was achieved for 20 samples; their phylogenetic analysis (E2 protein) revealed the presence of ECSA lineage and reinforced the phylogenetic relationship between ECSA and Indian Ocean lineages. CONCLUSIONS: The genomic surveillance of CHIKV showed that only ECSA lineage circulated in Bahia since the 2014 outbreak.


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Virus Chikungunya/genética , Genoma Viral/genética , Fiebre Chikungunya/virología , Filogenia , Brasil/epidemiología , Brotes de Enfermedades , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa , Monitoreo Epidemiológico , Fiebre Chikungunya/epidemiología , Genotipo
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