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Objective To investigate the clinical value of whole brain CT perfusion imaging combined with head and neck CTA in the diagnosis of acute ischemic stroke.Methods From November 2016 to November 2018,the clinical data and medical imaging data of 220 patients diagnosed as acute ischemic stroke in the Department of Neurology,Dajiangdong Hospital were selected.All patients underwent CT scan followed by a CT perfusion scan and a routine cranial CTA.The radiation dose was recorded.The ischemic lesions and their stenosis were analyzed by CTA.CT perfusion imaging was used to analyze regional cerebral blood flow imaging (rCBF),tissue perfusion (rCBV) and mean passage time (MTT) in all patients..And the test performance of the two inspection methods was compared.Results CTA was used to analyze vascular stenosis.The stenotic vessels were mainly distributed in the M1 ～ M3 segment (3 cases of them were completely obstructed,11 cases were obstructed ≥50％,19 cases were 30％ ≤ stenosis ＜ 50％),and A1 ～ A3 segments (4 cases of them were obstructed,7 cases were 30％ ≤ stenosis ＜ 50％),and basilar artery (2 cases of them occlusion,6 cases of ≥ 50％,11 cases of 30％ ≤ stenosis ＜50％).CT perfusion examination was performed in the whole brain.The rCBF of the control area was higher than that of the ischemic penumbra and higher than the infarct area.The rCBF values were (50.31 ± 11.21) 100 g/min,(34.45 ±22.17)100 g/min and (6.87 ± 3.52)100 g/min,respectively,the difference was statistically significant (t =17.81,19.14,all P＜0.05).The region rCBV of the control area was higher than that of the ischemic penumbra and the infarct region,and the rCBV values were (3.35 ± 1.01) mL/100g,(2.87 ± 0.55) mL/100g and (6.87 ± 0.51) mL/100g,respectively,the differences are statistically significant (t =6.47,9.19,all P ＜ 0.05).The MTT in the control area was lower than that in the ischemic penumbra and the infarct area,and the MTT values were (4.52 ± 1.21) s,(7.88 ± 1.01) s and (11.81 ± 1.18) s,respectively,the differences are statistically significant (t =10.50,13.54,all P ＜0.05).The two methods were compared for consistency,and the kappa value was greater than 0.75,showed a high degree of consistency.Conclusion CT perfusion imaging and CTA have little difference in the diagnostic efficacy for patients with acute ischemic cerebral infarction,and can accurately diagnose the disease.CT perfusion imaging can determine the location of the ischemic penumbra,and CTA can be analyzed based on the stage of the diseased vessel.Both two methods can play different guiding role for individualized treatment.
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Objective To survey the influence of nursing intervention on cognition level for pressure sores and psychological state among accompany family members of patients with cerebral injury. Methods 123 accompany family members of patients with cerebral injury were selected and took part in the investigation about cognition level for pressure sores, besides, SDS and SAS were also adopted to evaluate their psychological state. Later nursing intervention was given to increase their cognition level for pressure sores, then another evaluation was carried out. Results before and after the intervention were compared. Results The accompany family members lacked knowledge of pressure sore, showed serious anxiety and depression for nursing pressure sore before intervention. But their cognition level for pressure sore improved and anxiety and depression lightened after intervention. Conclusions Nursing intervention is effective to alleviate cognition level for pressure sore and psychological state among accompany family members of patients with cerebral injury, which is worthy of clinical application.
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Synthetic pesticides-pyrethroids have been widely used in agriculture and in households. Most of them are the environmental hormone substances. Pyrethroids have toxic effects on animals and humans,inducing teratogenicity,carcinogenicity and mutagenicity. In the present paper,the typical animals-fish,mice and rats were choosen for the health risk assessment,and the research progresses on adverse effects of pyrethroids in nervous toxicology,physiological and biochemical toxicology,reproductive toxicology were summerized,as well as the effects of the animal enzymes and immune system.