Effect of different sterilization on contents of effective components in Zhining Oral Solution / 中成药

Objective:To find a suitable sterilization for the Zhining oral solution. Methods:The contents of effective components in Zhining oral solution with the different sterilizations were determined by HPLC.Results: Pasteurization and flowsteam sterilization have little effect on the contents of effective components in Zhining oral solution, while autoclave sterilization and 60 Co radiation sterilization reduced respectively the contents chrysophanol or 2,3,5,4′ tetrahydroxystilbene 2 O ? D glucoside. Conclusions: The different sterilizations have different effects on contents of effective components. Zhining oral solution should be sterilized by pasteurization.