RESUMEN
Evaluation and distribution of established etiological risk factors in patients of breast cancer in our local population. Institution based non-interventional descriptive and prospective study Department of Pathology, Liaquat University of Medical and Health Sciences, Jamshoro from January 2009 to December 2011. One hundred and two cases of breast cancer diagnosed on HE staining were selected for the study. More than 50% were in 4th and 5th Decades of life. 94% were married and 06% were un-married. 65% were in pre-menopausal group and 35% in post-menopause group. 93% had positive history of breast feeding. None of them had ever taken oral contraceptive. Smoking history was present only in 9.80% cases. 27% cases had family history of breast cancer in first degree relative and 13% in 2nd degree relatives. Majority [66.66%] were belongs to lower middle socioeconomic class. Surprisingly in this study marital status, parity, and breast feeding not proved as protective factors against breast cancer