The relationship between KAI1 gene and neoplastic invasion, metastasis, prognosis / 医学研究生学报

KAI1 gene is a metastasis suppressor gene discovered in 1995, the product of which is a member of the transmembrane-4 superfamily. The expression of KAI1 gene correlate with metastasis of almost all cancer. But some results of some study are different. This article reviewed the study of the genomic structure of KAI1 gene and the relationship between KAI1 gene and neoplastic invasion, metastasis, prognosis.