RESUMEN
Q fever is a zoonotic infection caused by Coxiella burnetii. Acute Q fever usually develops as a self-limited flu-like illness, atypical pneumonia, or hepatitis. We experienced a case of Q fever in a 50-year-old male who had a prolonged fever. The bone marrow and lymph node biopsy revealed fibrin-ring granulomas, which is a distinct finding of Q fever. The diagnosis was proven by high titers of C. burnetii anti-phase II antibody (IgM 1:512 and IgG >,048) and positive nested PCR for the com-1 gene. Q fever is rare in Korea, but should be considered in the differential diagnosis of fever of unknown origin
Asunto(s)
Humanos , Masculino , Persona de Mediana Edad , Biopsia , Médula Ósea , Coxiella burnetii , Diagnóstico Diferencial , Fiebre , Fiebre de Origen Desconocido , Granuloma , Hepatitis , Inmunoglobulina G , Corea (Geográfico) , Ganglios Linfáticos , Neumonía , Reacción en Cadena de la Polimerasa , Fiebre QRESUMEN
Nocardiosis is well-known opportunistic infection in immunocompromised patients. The timely diagnosis and treatment, however, is still a difficult problem. Recently, as newer molecular techniques, particularly 16S rRNA sequencing, are implemented, the diagnosis and management of the infection are improving. We report a case of lung abscess in a 39-year-old-man who underwent kidney transplantation. He was diagnosed of Nocardia elegans by 16S rRNA sequencing and was cured of the infection with appropriate antibiotic therapy.
Asunto(s)
Huésped Inmunocomprometido , Riñón , Trasplante de Riñón , Pulmón , Absceso Pulmonar , Nocardia , Nocardiosis , Infecciones OportunistasRESUMEN
Cryptococcosis is a disseminated infection caused by Cryptococcus neoformans. It usually causes pulmonary infection and meningitis in immunocompromised patients. However, osteomyelitis due to C. neoformans is extremely rare. It is generally known that cryptococcal osteomyelitis is a complication of disseminated cryptococcosis, appearing in 5-10%. We experienced a case of cryptococcal osteomyelitis with paraspinal abscess in a liver transplant patient.
Asunto(s)
Humanos , Absceso , Criptococosis , Cryptococcus neoformans , Huésped Inmunocomprometido , Hígado , Meningitis , Osteomielitis , TrasplantesRESUMEN
Septic arthritis is an uncommon finding of invasive Aspergillosis. It can be caused by direct inoculation, post-surgical infection, and hematogenous spread. Articular aspergillosis often involves the knee. A 49-year-old man who received a liver transplant in China on two months ago, due to liver cirrhosis caused by hepatitis B virus was admitted because of left side hip pain. Hip MRI showed joint effusion and bony destruction of the left hip and acetabulum. Incision and drainage was done and Aspergillus fumigatus was isolated from the resected tissue. After eight weeks of amphotericin B therapy, total hip replacement arthroplasty was done. Oral itraconazole 400mg/day was prescribed for six months after operation. The patient is now doing well without physical restriction
Asunto(s)
Humanos , Persona de Mediana Edad , Acetábulo , Anfotericina B , Artritis , Artritis Infecciosa , Artroplastia , Artroplastia de Reemplazo de Cadera , Aspergilosis , Aspergillus , Aspergillus fumigatus , China , Drenaje , Virus de la Hepatitis B , Cadera , Itraconazol , Articulaciones , Rodilla , Hígado , Cirrosis Hepática , Trasplante de Hígado , TrasplantesRESUMEN
Septic arthritis is an uncommon finding of invasive Aspergillosis. It can be caused by direct inoculation, post-surgical infection, and hematogenous spread. Articular aspergillosis often involves the knee. A 49-year-old man who received a liver transplant in China on two months ago, due to liver cirrhosis caused by hepatitis B virus was admitted because of left side hip pain. Hip MRI showed joint effusion and bony destruction of the left hip and acetabulum. Incision and drainage was done and Aspergillus fumigatus was isolated from the resected tissue. After eight weeks of amphotericin B therapy, total hip replacement arthroplasty was done. Oral itraconazole 400mg/day was prescribed for six months after operation. The patient is now doing well without physical restriction
Asunto(s)
Humanos , Persona de Mediana Edad , Acetábulo , Anfotericina B , Artritis , Artritis Infecciosa , Artroplastia , Artroplastia de Reemplazo de Cadera , Aspergilosis , Aspergillus , Aspergillus fumigatus , China , Drenaje , Virus de la Hepatitis B , Cadera , Itraconazol , Articulaciones , Rodilla , Hígado , Cirrosis Hepática , Trasplante de Hígado , TrasplantesRESUMEN
Nocardiosis is well-known opportunistic infection in immunocompromised patients. The timely diagnosis and treatment, however, is still a difficult problem. Recently, as newer molecular techniques, particularly 16S rRNA sequencing, are implemented, the diagnosis and management of the infection are improving. We report a case of lung abscess in a 39-year-old-man who underwent kidney transplantation. He was diagnosed of Nocardia elegans by 16S rRNA sequencing and was cured of the infection with appropriate antibiotic therapy.
Asunto(s)
Huésped Inmunocomprometido , Riñón , Trasplante de Riñón , Pulmón , Absceso Pulmonar , Nocardia , Nocardiosis , Infecciones OportunistasRESUMEN
Cryptococcosis is a disseminated infection caused by Cryptococcus neoformans. It usually causes pulmonary infection and meningitis in immunocompromised patients. However, osteomyelitis due to C. neoformans is extremely rare. It is generally known that cryptococcal osteomyelitis is a complication of disseminated cryptococcosis, appearing in 5-10%. We experienced a case of cryptococcal osteomyelitis with paraspinal abscess in a liver transplant patient.