[Frequency of colorectal tumors among patients who underwent colonoscopy in Imam Khomeini hospital, Ardabil, Iran from November 2008 to September 2010]

Colorectal cancer is the most common cancer and the second leading cause of cancer deaths. Annually it is the cause of more than 500000 deaths worldwide. Therefore, detection and treatment of these tumors could potentially enhance recovery and improve prognosis. This study determines the frequency of colorectal tumors among patients who underwent colonoscopies in Imam Khomeini Hospital, Ardabil, Iran. This retrospective cross-sectional study was performed on 853 patients who underwent colonoscopies in Imam Khomeini Hospital from November 2008 to September 2010. All patients were evaluated for demographic variables, location and size of tumors by a checklist. The collected data were statistically analyzed by tables, graphs and student's t-test with SPSS v. 16 software. Among 853 patients who were studied, 432 [50.87%] were females and 419 [49.13[y0] were males. Of these, 45.4% were less than 50 years of age. The most common cause for patient visits were rectal bleeding [34.5%] and abdominal pain [20.2%]. The most common complaint among patients with colorectal lesions seen in colonoscopies were rectal bleeding [54.2%], abdominal pain [18.75%], anemia [10.4%], diarrhea [8.3%], and constipation [8.3%]. Of all colonoscopies performed, 37.2% were normal. Lesions of the right colon were seen in 27.08% and 72.9% were in the left colon. According to results of this study and the frequency in detecting colorectal tumors, the performance of retrospective studies based on disease risk factors could be effective in decreasing future disease cases

evaluation of ovarian cancer symptoms and risk factors in patients of hazrat-e-rasool and Shahid Akbarabadi hospitals

Ovarian cancer is the most fatal gynecologic malignancy. New methods for detecting this cancer, has no significant effect on patients survival. One of the most important reasons is this fact that patients detect lately. Therefore identification of this cancer symptoms and signs can be effective in its early diagnose and reduction of mortality. This investigation was a cross sectional study that was performed on 89 patients with ovarian cancer and 89 people as control group. The collection of data was done to according of questionnaire of ovarian cancer risk factors and patients complains. Then data was compared between two groups and analyzed by SPSS version 16 software. The incidence of ovarian cancer was 0.67%. 20.8% of patient group had infertility or nulliparity history. Incidence of cancer in these patients significantly was more than other in this group [p=0.03]. Using oral contraceptive has a prophylactic effect [p<0.01]. The correlation between breast cancer history and incidence of ovarian cancer was significant [p<0. 01]. Abdominal pain, sense of abdomen or pelvic mass, infertility, gastrointestinal problems and abnormal uterine bleeding must be considered as other important symptoms as well. According to results of investigation, incidence of mentioned symptoms must be noticed for rule out of ovarian cancer, specifically in patients who have ovarian cancer risk factors

[Evaluation of correlation between maternal serum level of beta-human chorionic gonadotropin during 16-20 weeks of pregnancy and preeclampsia incidence]

Most current hypotheses Background: regarding the pathophysiologic mechanisms of preeclampsia point to early placental abnormalities. Therefore, we attempted to determine whether maternal human chorionic gonadotropin [hCG] levels in second trimester predict preeclampsia. In this prospective study, 508 pregnant women who referred to Shahid Akbar Abadi prenatal clinic for prenatal care during 2007-2009 were enrolled. Maternal serum hCG was measured of all these women during 16-20 wks of gestational age. All these women were followed and evaluated for preeclampsia. In 47 women [9.3%], preeclampsia was detected. The mean of log serum hCG levels during second trimester of pregnancy were found to be significantly higher in severe preeclampsia, compared with controls [p<0.05]. Furthermore, increase of maternal age enhances risk of preeclampsia. Our finding indicates that a serum level of maternal hCG during weeks 16-20 pregnancy, could be a value for predicting of preeclampsia

[Evaluation of correlation between maternal serum level of beta-human chorionic gonadotropin during 16-20 weeks of pregnancy and preeclampsia incidence]

Background: most current hypotheses Background: regarding the pathophysiologic mechanisms of preeclampsia point to early placental abnormalities. Therefore, we attempted to determine whether maternal human chorionic gonadotropin [hCG] levels in second trimester predict preeclampsia

Materials and Methods: in this prospective study, 508 pregnant women who referred to Shahid Akbar Abadi prenatal clinic for prenatal care during 2007-2009 were enrolled. Maternal serum hCG was measured of all these women during 16-20 wks of gestational age. All these women were followed and evaluated for preeclampsia

Results: in 47 women [9.3%], preeclampsia was detected. The mean of log serum hCG levels during second trimester of pregnancy were found to be significantly higher in severe preeclampsia, compared with controls [p<0.05]. Furthermore, increase of maternal age enhances risk of preeclampsia

Conclusions: our finding indicates that a serum level of maternal hCG during weeks 16-20 pregnancy, could be a value for predicting of preeclampsia