Effect of catharanthus roseus, Don, extracts on trichophyton mentagrophytes

The effects of the watery and alcoholic extracts of Catharanthus roseus leaves on Trichophyton mentagrophytes infection of cats and humans was investigated. The watery extract has no clearing therapeutic effect on the infection in both animals and patients. The alcoholic extract of the plant leaves at a concentration of 4% gave a notable effect. It caused complete healing of 83.3% of the affected cats and 77.8% of patients with Tinea pedis due to Trichophyton mentagrophytes infection. The treatment was by local application for four weeks. No side effects were detected during the period of treatment

Gastroduodenal changes in collagen diseases

The aim of this study was to study macroscopic and microscopic changes occuring in gastric and duodenal mucosa of patients suffering from collagen diseases with gastro-intestinal symptoms and also to show if these changes are due to the disease itself or the side effect of anti inflammatory drugs used in the treatment.We found that changes in the form of gastritis duodenitis, congestion, erosions and ulceration are more common in long standing cases than early discovered cases. Also we showed the presence of thickneing of basement membrane of gastric and duodenal mucosa denoting the presence of immune complex deposition and favouring the role of the collagen process as an etiology for gastro-duodenal changes

hepatotoxic effects of petroleum refining products on workers exposed to such hazards

The present study was carried to verify the effect of petroleum re-refining products on the workers exposed to it [50] subjects. Liver function tests, prothrombin time, S.G.P.T. gamma-GTP were done for every case. Ultrasonongraphy was done for those cases with high. Gamma-G.T.P. level, the results were analysed and compared to those done for 20 normal control subjects