RESUMEN
Researches show that substance abuse, AIDS and their interaction have negative effects on people. The aim of the present study was to investigate psychological disorders as well as quality of life of 4 groups of men: drug-using, drug-using HIV-infected, non-drug using HIV infected and a reference group of healthy men. Study samples consisted of 350 subjects from 4 groups of men: drug-using, drug-using HIV infected non-drug using HIV infected and a reference group of healthy men [100 in each group except for the reference group which consisted of 50 subjects]. Study was applied by means of SCL-90 and SF-36 questionnaires. Multivariate Analysis of Variance [MANOVA] was employed in order to compare the data obtained from the four groups of subjects. Results of the study showed that there were significant differences among the four groups of the subjects in all of the components of SF-36 and in all of the SCL-90 scales. Compared to the healthy group of subjects, drug-using, drug-using HIV infected and non-drug using HIV infected had higher scores in SCL-90 questionnaire and lower scores in SF-36 questionnaire. Substance abuse and AIDS have negative effects on individuals' psychological health and quality of life. To prevent substance abuse, AIDS, and their negative effects, comprehensive programming and creation of a new understanding of these two are essential