Histopathological changes of the ossicles in case of suppurative otitis media

10 ossicles [8 incus and 2 mallei] were removed during middle ear surgery. Also, normal ossicles were removed from reentally dead cadavers. The specimens were prepared histologically. Histopathological changes were found affecting the epithelium enveloping the ossicles with complete or partial replacement of the marrow spaces by dense fibrous tissue. Also, histopathological changes were found in the blood vessels of the bone marrow. Subsequently, it is advised not to use the autograft in ossiculoplasty