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Sudan Medical Journal. 2009; 45 (1): 35-41
en Inglés | IMEMR | ID: emr-104839

RESUMEN

To determine the risk factors for bleeding from asymptomatic varices secondary to schistosomal portal hypertension. This is a retrospective, prospective, longitudinal, hospital, based study in a specialised portal hypertension clinic. Clinical, biochemical, haematological, endoscopic and sonographic evaluation were performed. Data was collected prospectively in a special portal hypertension folder designed for the purpose. 141 patients, 104 males and 37 females with an age range of 12 to 72 years [mean 33.7 +/- 13.7] were studied. They were followed-up for a minimum of 1 year and a maximum of 6 years [mean 27.6 months]. 21 patients [14.9%] bled from their varices. 11 patients [7.8%] bled within one year and 10 within the subsequent 6 years. The interval between presentation and bleeding ranged from 4 days to 78 months [mean 19.9 +/- 21.6]. Of the 21 who bled, 3 rebled [14.3%] within 1 year. The bleeders had significantly longer duration of schistosomiasis [p <0.05], more serum bilirubin above 2mg% [p<0.01], more thrombocytopenia [p <0.05], more grade III and IV varices [p <0.05] and more grade III periportal fibrosis [p <0.01]. It is suggested that patients with these risk factors should be considered for close follow-up and medical treatment

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