Omental caking: a rare manifestation of malignant peripheral nerve sheath tumour

Malignant peripheral nerve sheath tumour [MPNST] is a very rare tumour with an incidence of one per 100,000 and constitutes between 3 to 10% of all soft tissue sarcomas. Most of the sarcoma involve the extremities and retroperitoneal regions. However, this case presented with mass in left inguinal region and then spread rapidly to omentum, assuming the appearance of an omental cake. Mass responded well to chemotherapy comprising of Ifosfamide and Doxorubicin

Porocarcinoma: a rare sweat gland malignancy

Eccrine Porocarcinoma [ECP] is a malignant tumour arising from the intraepithelial ductal parts of the sweat gland. It has also been described as malignant hidroacanthoma simplex, sweat gland carcinoma, malignant intra-epidermal eccrine poroma, eccrine poroepithelioma, dysplastic poroma, malignant syringo acanthoma and porocarcinoma. Treatment with wide local excision but metastatic lesions can be treated with chemotherapy. Here, we present a case report of 52 years old male who presented with a fungating growth on left pre-auricular region that came out to be a case of ECP on histopathological examination

Hepatic and skeletal metastases from primary intracranial atypical meningioma

Meningioma constitutes 27% of primary CNS tumours. It rarely metastasizes to distant sites [< 0.1%]. Here, we present a case report of primary atypical intracranial meningioma metastasizing to liver and bone after 4 years of surgery and postoperative radiotherapy presenting with multiple episodes of hypoglycemia

Correlation of perfusion and contractility of left ventricle myocardium on gated myocardial perfusion scintigraphy

Gated Single Photon Emission Computerized Tomography [SPECT] is a modality which is helpful in the detection of wall motion, thickening and ejection fraction of left ventricle. The purpose of this study was to correlate the ungated and gated SPECT in evaluation of left ventricle dysfunction. It was a prospective study done at Institute of Radiotherapy and Nuclear Medicine [IRNUM], Peshawar, in 2001/02. 76 patients [47 male and 29 female] with an average age of 52 +/- 11 years were inducted in this study. All patients underwent two days stress-rest Tc-99m MIBI [Methoxy Isobutyl Isonitrile] gated SPECT scan where 1110 MBq [30 mCi] was injected intravenously. Eight frames gating technique [variable fixed temporal resolution] of ECG was used to gate the cardiac cycle and whole acquisition was completed in 30 minutes. This technique very well evaluated the perfusion as well as wall motion/thickening [W/M/T] status of left ventricle. Out of 76 scans, 30% were normal, 22% transmural infarct, 25% partial thickness infarct, and 22% reversible ischemia. By doing the 20 segmental analyses, total 1520 segments were analyzed that

evealed good concordance of perfusion with W/M/T in 78% of segments while 22% segments showed poor concordance. Out of these 22%, 12% were having more wall motion abnormalities than that of perfusion, while in 10%, it was vise versa. Results of this study shows good correlation between gated and ungated SPECT for evaluation of left ventricle dysfunction [r = 0.73, p