Anti diabetic activity of the bark of parkinsonia aculeata in streptozotocin induced diabetic rats.

The extraction of the bark of Parkinsonia aculeata, family Leguminosae was carried out using benzene, chloroform, ethanol and distilled water in succession. The presence of alkaloids, flavonoids, tannins, steroids, and reducing sugars was confirmed during preliminary phytochemical screening. The extracts were evaluated for antidiabetic activity. The chloroform and ethanol extracts showed significant antidiabetic activity.

Anti-fungal activity of leaf extract of derris indica.

The extraction of the leaf of Derris indica, family Fabaceae was carried out using petroleum ether and chloroform in succession. The petroleum ether and choloform extracts showed the presence of phytosterols and saponins. The chloroform and ethanolic extracts showed the flavonoids and fixed oils the ethanolic and aqueous extracts showed the presence of carbohydrates. The extracts were evaluated for anti-fungal activity. The chloroform extract showed significant anti-fungal activity.

Synthesis, characterization and evaluation of antibacterial and antifungal activity of triazole derivatives of gallic acid.

Heterocycles bearing a symmetrical triazole represent an interesting class of compounds possessing a wide spectrum of biological activities such as antiinflammatory, anticancer, antitubercular, antiviral and antimicrobial properties. In present study an attempt was made to synthesize compounds using propyl gallate and hydrazine hydrate as starting material. And following the scheme five different compounds using different aromatic substituents. Synthesized compounds were subjected to physical characterization and spectral analysis for structural confirmation. The compounds were than subjected to evaluation of antibacterial and antifungal activity. The bacterial screening indicated that among the test compounds number S2, S3, moderately activity against all the tested bacterial strains Bacillus subtilus, Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae. The remaining compounds were found to be less active. Minimum inhibitory concentration value of the compounds against the bacteria stains reveals that compound S3, S4 have better onset of action against all bacteria strains as compared to that of standard. Antifungal screening revealed that the test compounds showed moderate activity against Aspergillus niger.