Mechanisms of bacterial resistance

The antibiotic resistance in microorganisms is a worldwide problem that results due to chemotherapy of microbial diseases. The appearance of gradual resistance shows that a single antibiotic loses its effectiveness with the laps of time against microorganisms. Bacteria: may develop resistance intrinsically or acquire it either vertically or horizontally. This review highlights the mechanisms involved in the resistance development-of bacterial species against different classes of widely used antibiotics