[Evaluation of associated anomalies with imperforated anus in 10 years study [1999-2008] in children hospitalized at Ali-Asghar Hospital]

Imperforate anus is a common anomaly associated with many other anomalies. The aim of this study is determining the frequency of associated anomalies in children with imperforated anus. This retrospective, cross sectional study was conducted over 245 neonates and children [137 male, 105 female and 3 ambiguous genitalia] with imperforated anus diagnosis, in Ali-Asghar Hospital 1999-2008. Our information was extracted from patients' records. SPSS 17 was used for data analysis. 50.6% of the patients had associated anomalies including 18% cardiovascular, 15.5% renal, 14.7% gastrointestinal, 13.9% vertebral, 13.1% genitourinary, and 8.2% external genitalia. The most prevalent associated anomaly was genitourinary system anomalies followed by cardiovascular anomalies. Patients with imperforated anus should undergo a detailed general physical, systemic and radiological examination [infant gram, echo cardiography, ultrasonography of urogenital system] in neonatal period for on time detection of associated anomalies

[Ambiguous genitalia and review of the cases]

Ambiguous genitalia is an important medical problem, so the physicians who see newborns should note to its urgent diagnosis and early decision for rearing gender. The subject of this article is describing the different types of disorders of sex development [DSD], its new classification and approach to the patients. The prevalence of its different types in 282 patients who was seen during 20 years is also reported. 46,XX DSD was the most prevalent type and 97.6% of it was due to congenital adrenal hyperplasia. 46,XY DSD and sex chromosome DSD were seen in 9.2% and 1.4%, respectively

relation between clinical manifestation and pathological reports of acute appendicitis in children admitted in Hazrat Ali Asghar hospital

Acute appendicitis is one of the commonest medical emergencies in children. Due to rapid progression of the disease and difficulty in diagnose, different paraclinical method including ultrasonography, radiology and CT scan etc, have been used in order to diagnosis the disease at early stage and thus prevent from any related complications. However; because of unavailability of the above mentioned paraclinical procedures in certain areas and/or its high cost, evaluation of clinical manifestation is very important in determining the severity of the disease. In this study the clinical manifestation of children, who had undergone surgery with the diagnosis of acute appendicitis, was compared with the pathological report, In this way by everything the clinical features, the progressing of the disease could be estimated, to large extent by pathology and thus decision in regard to surgery would be taken. In this study 58 children [including both girls and boys] between the ages of 3.5 year 14 with the primary diagnosis of acute appendicitis underwent surgery. As a retrospective study, the medical files of the patients were reviewed and the clinical features were compared with the pathological reports. Clinical manifestation and the pathological reports were comparable with each other according to results, increase in security of clinical features was associated with more rapid progression of pathology. In case of unavailability of Paraclinical methods such as ultrasonography and CT-scan more attention must be paid to clinical history and clinical sign and symptoms observe in a child suspected of having acute appendicitis. By this method, early diagnosis could be accelerated and any decision in regard to surgery would be taken accurately. As a result of unpleasant complications are prevented