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Background: There has been an alarming rise in the incidence of various diseases including that of cancer in the world with increase in the incidence of cutaneous malignancies owing to various changes that have taken place in the society over the past few years with respect to the culture, the lifestyle and also a contributory role has been played by the changes in the atmosphere as a result of increase in the air pollutants in the environment. Based on the scenario, we decided to conduct a study to evaluate the presentation and the management cutaneous malignancies in a teaching hospital set up in central india.Methods: A retrospective study was conducted between the time period of 1 year on the records of patients who were diagnosed with cutaneous and related malignancies who were treated at our Institute on a predesigned semi structured performa. SPSS version 23.0 was used for the analysis of the data collected.Results: We evaluated a total of 29 cases, Squamous cell carcinoma (SCC) was the most common histological type (51.72%) followed by melanoma (27.59%) and basal cell carcinoma (BCC, 20.69%). 75.86% of patients with cutaneous malignancies were males and 24.14% were females. Mortality rate observed was 13.7%.Conclusions: The most common cutaneous malignancy seen in this study was squamous cell carcinoma having increased propensity towards males than females. Rate of loco-regional disease and median disease-free survival is directly dependent on the adequacy of disease-free surgical margin and to the limited extent on the adjuvant therapy.
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Background: Laparoscopy involves insufflation of the abdomen by gas so that the endoscope can view the intra-abdominal contents without being in direct contact with the viscera or tissue. Access to the abdomen is the one challenge of laparoscopy that is particular to the insertion of surgical instruments through small incisions. Materials and Methods: The study was a prospective, randomized, double-blind, and comparative study conducted on 100 consenting patients who underwent laparoscopic surgeries at Father Muller Medical College Hospital, for a period of 3 years from December 2014 to 2017 for various conditions needing laparoscopy who fulfilled a pre-determined the inclusion and exclusion criteria. Results: In our study, the least age was 20 years, and maximum age was 61 years. Age ranged from 18 to 65 years with mean age of 40 years. Most cases were males 86%. There was no difference in the two groups in terms of demography and perioperative factors such as type of surgery and body mass index; hence, the data were statistically comparable. The mean time needed to create pneumoperitoneum was 2.31 ± 1 min in Veress needle technique and 3.99 ± 1 in open method (P = 0.000) gas leak was observed in 11 patients in open group whereas no patient had a gas leak in Group B (P = 0.000). Pneumoperitoneum was achieved in all 100 cases. There were 7 cases of abdominal wall hemorrhage 4 acute that was managed laparoscopically by harmonic cauterization. No vascular injury, bowel, omental was noted in both groups. Neither open nor closed needed with conversion to open due to inadequate access into the peritoneal cavity. One closed as access could not be gained was converted to open method. 3 (6%) patients had post-operative hematoma at the umbilical port site in open Group A whereas no one developed this complication in a closed group 9 (9%) patients presented with surgical site infection at the umbilical trocar site and 4 in the closed group
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Introduction: Diabetic foot is considered as one of the dreaded complications of diabetes mellitus and the most common cause of lower limb amputations. There are various studies done which show that uric acid is an inflammatory factor could have a role play in the development of a role in endothelial dysfunction. In view of the above said facts that we considered this study to see if there is any association between serum uric acid level and diabetic foot. Materials and Methods: A prospective cross-sectional analytical was conducted on 42 diabetic foot patients who met the inclusion criteria. Venous blood samples were obtained in fasting state for determinations of serum creatinine, uric acid, and hemoglobin A1c 24-h urine protein. Statistical Analysis: Results were expressed as mean ± standard deviation, and all the results which will be having a P < 0.05 was considered as considered as statistically significant; the mean age of the patients was 58 ± 8.3 years. Mean ± standard error (SE) of serum creatinine was 068 ± 0.038 mg/dL and mean ± SE of serum uric acid was 4.9 ± 0.10 mg/dL. In this study, there was no significant difference of serum uric acid, glycosylated hemoglobin, and renal functions between males and females (P > 0.05). There was a significant positive association between body mass index and serum uric acid (P < 0.001). After adjustment for weight, a significant positive association of serum uric acid level with diabetic foot was seen (P < 0.001). Conclusion: Serum uric acid had a significant positive association with diabetic foot.
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Introduction: Sonography is the most commonly performed investigation in surgical practice, and fatty liver is the most common finding in routine screening of the abdomen. The liver is considered as the recycler of the human body. An organ par excellence, which has undertaken the task from the basic like nutrition provision in starvation to the utmost complicated one like detoxification. This organ is the brunt taker of the body being the recycler and detoxifier. Aim: In our study, we aimed at finding the incidence of fatty liver in symptomatic individuals and corelating with the lipid profile we also followed these patients who had normal lipid profile for a minimum period of 1-year to see if there were any changes in the lipid profile latter. Materials and Methods: This was a prospective cross-sectional study conducted at a medical college in South India. The study was conducted between January 2013 and December 2015. The study included 130 healthy individuals who were willing to part-take in the study after fulfilling a pre-defined criterion. The patients underwent ultrasonography of the abdomen to evaluate the liver; those found to have fatty liver were further evaluated for lipid and sugars. The data were analyzed. Results: Among the 130 participants, we found that 86 had fatty liver of which 25 had abnormal lipid profile, 16 were found to have acanthosis nigrans with impaired glucose, 8 were newly detected diabetes mellitus, and 3 were found to have hypothyroidism. Eight had both impaired glucose and lipid abnormalities. The 26 patients who had normal laboratory values were followed for a year and were found to have normal laboratory functions. Conclusion: Fatty liver found on routine scanning the abdomen for other causes need to be evaluated.