Diagnosis of peripheral lung lesions by CT guided biopsy versus thoracoscopic biopsy

This work aimed to evaluate diagnostic accuracy of percutaneous CT guided biopsy versus thoracoscopic lung biopsy in realizing the etiology of peripheral lung lesions. The study included 40 patients with peripheral lung lesions. The patients subjected to the clinical history and examination, plain X-ray chest, routine laboratory investigations, CT guided biopsy and thoracoscopic lung biopsy. The final diagnosis in both groups were 32 malignant lesions and 8 benign lesions with a sensitivity of CT guided biopsy 75% and specificity 100%, while the sensitivity and specificity of thoracoscopic biopsy was 100%. Thoracoscopic biopsy is an important tool in diagnosing peripheral lung lesions whether small or large. Thoracoscopy provides higher degree of sensitivity in diagnosis of peripheral pulmonary lesion versus CT guided biopsy

Study of pulmonary complications after post mastectomy radiotherapy in patients with cancer breast treated with or without simultaneous adjuvant anti - estrogen

Forty women who were treated with postmastectomy radiotherapy for breast cancer with or without adjuvant tamoxifen treatment were involved in this study. Postmastectomy radiotherapy cases showed slight restrictive ventilatory abnormalities in pulmonary functions, mainly in patients received tamoxifen treatment. The radiological abnormalities developed with postmastectomy radiotherapy were more often easily detected by high resolution computed tomography [HRCT] than by CXR and these abnormalities were significantly higher in patients received tamoxifen treatment. Postmastectomy radiotherapy encountered has in the form of pneumonitis early and late pulmonary lung fibrosis