Effects of the organophosphorus pesticide Folisuper 600 (methyl parathion) on the heart function of bullfrog tadpoles, Lithobates catesbeianus (Shaw, 1802)

Abstract The aim of this work was to evaluate whether the heart function of bullfrog tadpoles (25 Gosner stage) is affected by their acute exposure (48 h) to a sub-lethal concentration (10 µg.L1) of the active principle of the organophosphorus pesticide Folisuper 600R (methyl parathion - MP). Our results demonstrated that MP causes not only a reduction in tadpoles cardiac ventricular mass, resulting in a marked reduction in their cardiac twitch force, but also impairs their swimming performance, irrespective of increasing their heart rate. Together, these findings indicate that low and realistic concentration of MP have a negative impact on tadpoles performance, jeopardizing their survival.

Resumo O objetivo do presente estudo foi avaliar se a função cardíaca de girinos de rãs-touro (estágio 25 de Gosner) é afetada pela exposição aguda (48h) a uma concentração sub-letal (10 µg.L1) do princípio ativo do pesticida organofosforado Folisuper 600R (metil paration MP). Nossos resultados demonstraram que o MP ocasionou não apenas uma redução na massa ventricular cardíaca dos girinos, como também provocou uma redução na sua força de contração cardíaca e de seu desempenho natatório, a despeito de ter sido observado um aumento de sua freqüência cardíaca. Conjuntamente, os achados aqui obtidos indicam que uma baixa e realística concentração de MP exerce um impacto negativo sobre o desempenho dos girinos, ameaçando sua sobrevivência.

Effects of the organophosphorus pesticide Folisuper 600 (methyl parathion) on the heart function of bullfrog tadpoles, Lithobates catesbeianus (Shaw, 1802) / Efeitos do pesticida organofosforado Folisuper 600 (metil paration) sobre a função cardíaca de girinos de rã-touro, Lithobates catesbeianus (Shaw, 1802)

Abstract The aim of this work was to evaluate whether the heart function of bullfrog tadpoles (25 Gosner stage) is affected by their acute exposure (48 h) to a sub-lethal concentration (10 µg.L–1) of the active principle of the organophosphorus pesticide Folisuper 600R (methyl parathion - MP). Our results demonstrated that MP causes not only a reduction in tadpoles’ cardiac ventricular mass, resulting in a marked reduction in their cardiac twitch force, but also impairs their swimming performance, irrespective of increasing their heart rate. Together, these findings indicate that low and realistic concentration of MP have a negative impact on tadpoles’ performance, jeopardizing their survival.

Resumo O objetivo do presente estudo foi avaliar se a função cardíaca de girinos de rãs-touro (estágio 25 de Gosner) é afetada pela exposição aguda (48h) a uma concentração sub-letal (10 µg.L–1) do princípio ativo do pesticida organofosforado Folisuper 600R (metil paration – MP). Nossos resultados demonstraram que o MP ocasionou não apenas uma redução na massa ventricular cardíaca dos girinos, como também provocou uma redução na sua força de contração cardíaca e de seu desempenho natatório, a despeito de ter sido observado um aumento de sua freqüência cardíaca. Conjuntamente, os achados aqui obtidos indicam que uma baixa e realística concentração de MP exerce um impacto negativo sobre o desempenho dos girinos, ameaçando sua sobrevivência.

Enquête "connaissances, attitudes, pratiques" et séroprévalence VIH1 chez les prostituées et filles "libres" de Mbaimboum (Cameroun)

Cette étude confirme que le taux de séroprévalence pour l'infection à VIH1 est préoccupant dans cette région frontalière. La situation géographique exceptionnelle de ce village; et l'importance des transactions commerciales qui y sont effectuées en font un point de convergence pour des femmes se livrant à la prostitution. S'installe alors; une prostitution occasionnelle non contrôlée qui fait de ce village un foyer épidémique important et une source potentielle de dissémination. Ce modèle n'est pas unique et montre que l'épidémie gagne les zones rurales par l'intermédiaire des places marchandes ou il devient impératif d'apporter aux populations l'information et l'éducation nécessaires. Ainsi les prostituées et les filles libres sont des populations cibles qu'il conviendrait d'informer et d'éduquer rapidement et en priorité dans ces régions si l'on ne veut pas voir la situation exploser dans un avenir proche

Enquete C.A.P.C. et de sero-prevalence VIH 1 a Mbaimboum; marche frontalier du Nord-Est du Cameroun : etude en population generale

Cette etude montre que le taux de seroprevalence pour l'infection a VIH 1 est preoccupant dans cette region frontaliere. La situation exceptionnelle de ce village a la conjonction du Tchad; de la Republique Centrafricaine et du Cameroun; sur un axe de commerce avec le Nigeria laisse a penser que l'avancee se fait le long des axes routiers par l'intermediaire de la prostitution. Ainsi les prostituees; les filles libres et les camionneurs sont des populations cibles qu'il conviendrait d'informer et d'eduquer rapidement et en priorite dans cette region si l'on ne veut pas voir la situation exploser dans un avenir proche

Review of HIV prevalence studies in Cameroon; what next?

The number of HIV studies available in Cameroon are wide and varied. The analysis of the HIV seroprevalence data in Cameroon shows that HIV rates are increasing in the surveyed groups as well as in general population. Cameroon it can not be consider any more as HIV low prevalence country. Given the scarce resources and the variety of studies performed a point for reflexion is needed to conduct future epidemiological studies. Priorities need to be done; standard methods need to be established and integration within the health information system is advisable

A review of KABP studies on AIDS and HIV infection in Cameroon

The authors reviewed the studies on knowledge; attitudes; beliefs and practices regarding AIDS and HIV infection in Cameroon. Overall there is a clear increase on knowledge about AIDS among the different groups surveyed although misconceptions are still present which can lead to wrong attitudes towards infected people. The surveys undertaken to date have generally focused on knowledge and practices. More in depth qualitative data is necessary to understand sexual behavior. Behavior research should be linked to interventions to limit the increase of HIV infection

L'experience de filles libres educatrices a Yaounde dans la prevention des MST et du SIDA

Dans le cadre du Programme National de Lutte contre le SIDA au Cameroun; l'utilisation des filles libres educatrices a ete une des strategies adoptees ciblant les groupes a haut risque. Des resultats preliminaires ont ete presentes ailleurs et ont montre son positif impact. Afin d'evaluer cette strategie; une enquete de connaissances; attitudes; croyances et pratiques (ACP) aupres des filles qui pratiquaient la prostitution a Yaounde a ete faite. Cette enquete a eu pour but non seulement de faire le point sur les differentes actions educatrices menees aupres de ce groupe mais aussi de mettre sur pied des methodes d'education plus efficaces