RESUMEN
We report the success of oral cyclosporine therapy in a patient with severe vision-threatening vernal keratoconjunctivitis. A child presented with severe allergy which was not controlled with topical steroids, cyclosporine and mast cell stabilizers. Oral steroids were required repeatedly to suppress inflammation. Child showed a dramatic improvement and stabilization with oral cyclosporine therapy. Oral cyclosporine therapy can be tried in severe vision-threatening allergy refractory to conventional therapy.
Asunto(s)
Administración Oral , Niño , Conjuntiva/patología , Conjuntivitis Alérgica/diagnóstico , Conjuntivitis Alérgica/tratamiento farmacológico , Córnea/patología , Ciclosporina/administración & dosificación , Relación Dosis-Respuesta a Droga , Resistencia a Medicamentos/efectos de los fármacos , Estudios de Seguimiento , Glucocorticoides/uso terapéutico , Humanos , Inmunosupresores/administración & dosificación , Masculino , Estudios Retrospectivos , Índice de Severidad de la EnfermedadRESUMEN
We report a case of surgically induced necrotizing scleritis following pterygium surgery with the bare sclera technique, without the use of adjunctive irradiation or mitomycin C. The patient was successfully treated with systemic immunosuppression.
Asunto(s)
Femenino , Estudios de Seguimiento , Humanos , Inmunosupresores/uso terapéutico , Persona de Mediana Edad , Procedimientos Quirúrgicos Oftalmológicos/efectos adversos , Complicaciones Posoperatorias , Pterigion/cirugía , Escleritis/tratamiento farmacológicoRESUMEN
We report a case of nocardiosis in a 42, years male with common variable immunodeficiency syndrome (CVID). He presented with arthritis, subcutaneous abscess and pleural effusion. Diagnosis of CVID was made during this presentation. Serum IgG, IgA and IgM levels were markedly decreased. Nocardia asteroides was cultured from pleural fluid. He was successfully treated with intravenous immunoglobulin and cotrimoxazole.