RESUMEN
Background: atherosclerosis is a disease of the large and medium-sized arteries causing luminal narrowing [focal or diffuse]
Aim of the Work: measure the relationship between coronary artery disease complexity using SYNTAX score and peripheral arterial disease complexity using TASC II score
Patients and Methods: the study was designed as a prospective single center cross-sectional study conducted at Ain shams university hospitals. The study included 50 patients referred for elective coronary angiography in the time period from August 2016 till July 2017
Results and conclusion: patients with complex PAD had complex CAD. This finding suggested that PAD and CHD are different clinical manifestations of atherosclerosis and systemic pan vascular involvement is present in patients with complex lesions. [P-value 0.046]
RESUMEN
Chronic pulmonary hypertension [CPHT] has a great impact on both right ventricular [RV] systolic and diastolic properties and the assessment of those properties is not always feasible by traditional echocardiography examination. Tissue Doppler imaging [TDI] has recently emerged as a new, rapid and noninvasive tool for evaluation of RV systolic function. To determine the right ventricular systolic and diastolic function in patients with chronic pulmonary hypertension by tissue Doppler imaging and its correlation to conventional echocardiography parameters. The study included 30 consecutive patients with symptoms of right-sided heart failure due to CPHT who were in sinus rhythm, together with 10 normal subjects as controls. Pulsed-wave tissue Doppler imaging was used to measure peak systolic tricuspid annular velocity [Sa] as an index of RV function, peak early [Ea] and late [Au] diastolic tricuspid annular velocities. Among the 30 patients, 18 were females [60%] and 12 were males [40%]. Their mean age was 47.0 +/- 7.5 years. Among the 10 control subjects, 5 were males [50%] and 5 were females [50%]. The mean Sa velocity of the patient group was lower than the control group [9.57 +/- 2.06 vs. 15.05 +/- 1.75 cm/s., p < 0.001] signifying impairment of RV systolic function. The mean Ea velocity and the Ea/Aa ratio of the patient group was lower than the control group [9.85 +/- 3.21 vs. 17.95 +/- 2.27 cm/s., p < 0.001 and 0.98 +/- 0.58 vs. 1,54 +/- 0.18, p < 0.05 respectively], while the mean Aa velocity did not show any significant difference between the two groups [11.94 +/- 5.25 vs. 11.67 +/- 1.31 cm/s., p = NS]. In the patient group, there was a very good inverse correlation between both right ventricular diastolic dimension, right ventricular systolic pressure and Sa velocity as an index of RV systolic function [r = - 0.79, p < 0.001, and r = - 0.57, p < 0.001, respectively]. There was a very good correlation between E/A ratio of the trans-tricuspid Doppler flow and Ea/Aa ratio measured by TDI of the tricuspid annular motion "indices of diastolic function" [r = 0.79, p <0.001]. TDI is a new noninvasive method to detect systolic and diastolic dysfunction in patients with chronic pulmonary hypertension