RESUMEN
Background: Chronic Rhinosinusitis (CRS) places a relativelylarge socioeconomic burden on developed nations, yet remainsa difficult disease to treat. Vitamin D3 (VD3) deficiency isreported to be associated with increased incidence of allergicairway diseases. The ability of VD3 to augment innate andadaptive immune responses has sparked interest in itsimmunologic role in allergy. The objective of the present studyis to evaluate the relationship between serum vitamin D leveland Chronic Rhinosinusitis (CRS).Materials & Methods: A total of 25 patients with ChronicRhinosinusitis were enrolled and were labelled as study group.Also, 25 healthy subjects without history of sinusitis and noendoscopic evidence of inflammatory sinus disease wereenrolled as control group. Complete demographic details of allthe patients were obtained. Blood samples were obtained fromall the patients and were sent to laboratory for assessment ofVitamin D levels. In the laboratory, ELISA technique was usedfor assessment of serum Vitamin D levels. All the results wererecorded in Microsoft excel sheet and were analysed by SPSSsoftware.Results: Mean Vitamin D levels of the study group patientswas found to be 31.8 nmol/L and that of control group werefound to be 43.2 nmol/L respectively. Vitamin D levels weresignificantly lower in study group as compared to control group.Conclusion: Vitamin D levels are significantly altered inChronic Rhinosinusitis patients. However; their role inpathogenesis of the disease need further exploration.
RESUMEN
Background: Tracheo-bronchial foreign bodies continue topresent challenges to otolaryngologists. The major issuesinvolve the accurate diagnosis and speedy, safe retrieval of theforeign body. Accidental foreign-body aspiration in therespiratory tract can lead to considerable morbidity andmortality in both adults and children. Hence; under the light ofabove mentioned data, the present study was undertaken forassessing the prevalence of Tracheo- bronchial foreign bodycases.Materials & Methods: Data of a total of 250 patients wasanalysed during the study period. The overall prevalence oftracheobronchial foreign body cases was assessed. Completedemographic details of all the cases were obtained from thedata record files. Patient data, clinical history, radiographic andbronchoscopic findings were also obtained from their recordfiles for defining the epidemiology of the patients. Record ofPreoperative Chest X-ray was also obtained. All the resultswere recorded in Microsoft excel sheet and were analysed bySPSS software.Results: The prevalence of tracheobronchial foreign bodycases was 11.2 percent (28 cases). Needles were found in39.29 percent of the cases, while peanuts were found in28.57 percent of the cases. Plastic objects were found in 21.43percent of the cases. Right bronchial tree was involved in 39.3percent of the cases, while foreign body was found in leftbronchial tree in 28.57 percent of the cases. Tranche wasfound in 21.43 percent of the cases.Conclusion: Because of associated high mortality with foreignbody aspiration, it is required to rapidly recognize from thepatient's history and start the prompt by bronchoscopy andextraction of the aspirated foreign body.