RESUMEN
Background: Pomegranates contain chemical saponins and flavonoids while lemongrass stems have flavonoid chemical compounds. Substances that can inhibit the linking of bacteria are saponins and flavonoids. The most common microorganism found in ulcus diabetikum (ulcer diabetes) is Staphylococcus aureus. The purpose of this study was to determine the antibacterial activity of a combination of pomegranate ethanol extract and ethanol extract of lemongrass stems against S. aureus bacteria.Methods: This study used an experimental design with a complete randomized design study divided into 5 groups: groups 1 (75:25), 2 (50:50), 3 (25:75), positive control (tetracycline) and negative control. Manufacture of pomegranate peel extract and lemongrass stems was done by maceration method for further rotary, after the extract was obtained tested for antibacterial activity by diffusion method using a cylinder. With the test used analysis of variance one way.Results: The results of this study showed that the combination of pomegranate ethanol extract and citronella stem ethanol extract showed activity against S. aureus with a ratio of 15 ul:5 ul, 15 ul:15 ul, 5 ul:15 ul with inhibitory diameter of respectively 13 mm, 11 mm, 8 mm. Whereas for positive control with chloramphenicol, the inhibition area is 9 mm.Conclusions: Statistically the combination of pomegranate ethanol extract and lemongrass stems has antibacterial power which uses p=0.005 and p<0.05. The combination of pomegranate ethanol extract and lemongrass stems has very strong antibacterial activity against S. aureus due to inhibition zones of 10-20 mm.
RESUMEN
Background: Chronic obstructive pulmonary disease (COPD) is a disease that is a problem throughout the world where its prevalence, morbidity and mortality are increasing every year. The high number of COPD visits is due to persistent and progressive shortness of breath complaints. Existing pharmacological therapies for COPD have not shown improvement in the long-term decline in pulmonary function that is a hallmark of COPD. It is very necessary for companion therapy that is non-pharmacological treatment is expected to be able to complete pharmacological treatment in reducing shortness of breath of COPD patients with pursed-lip breathing exercise.Methods: This study uses a quassy experiment design with two group pretest and posttes design approaches. This study was in obstructive pulmonary disease patients in the lung hospital in West Sumatra with an intervention group of 16 and a control of 16 respondents. Data analysis using univariate and bivariate using independent t-test statistics.Results: The results showed the average decrease in shortness of breath in the control group without pretest 3.19 and posttest 2.56 in the pretest pursed lip breathing exercise intervention group 3.19 and posttest performed 1.69. Test statistic p-value 0.026.Conclusions: There is an effect of pursed lip breathing exercise on reducing the level of shortness of breath in patients with chronic obstructive pulmonary disease.