Prevalence of non-alcoholic fatty liver disease in diabetics in government Dharmapuri Medical College Hospital, Dharmapuri

Introduction: The incidence of diabetes in India is 3.8%34. It is well known that diabetes is a systemic disease; it affects almost all organ systems. Non-alcoholic fatty liver disease (NAFLD) is being increasingly recognized today as a potentially serious complication of diabetes, especially type 2. The spectrum of NAFLD extends from simple steatosis or steatosis with mild inflammation to severe non-alcoholic steatohepatitis (NASH). Aim of the study: The Aim was to analyse the prevalence of Fatty Liver (Non Alcoholic Fatty Liver Disease) in Patients with Diabetes. Materials and methods: The study was to be conducted in Government Dharmapuri Medical College Hospital, Dharmapuri, and Tamil Nadu. It was an observational type of study. Interview technique was used to collect information on a predesigned proforma. All diabetes patients both type 1 and type 2. Both male and female patients were included in the study. Results: Among the 75 diabetics who were studied, fatty liver was found in 31patients (41.33%). No. of patients with fatty liver was 31. No. of patients without fatty liver was 44. The number of males with fatty liver were 2 (2.6%) and females 29 (38.6%). The number of patients with fatty liver who had central obesity (waist hip ratio >1) was 23 (74.19%). All the patients with fatty liver had central obesity (waist hip ratio >1 in males and >0.85 in females). Conclusion: The prevalence of non-alcoholic fatty liver disease was 41.3% and it was present mainly in patients with type 2 diabetes mellitus. It occurred more commonly in women (38.66%) than men.

Mucinous cystadenoma of the lung presenting as localised bronchiectasis.

Mucinous cystadenoma is a very rare pulmonary neoplasm. Here we report the case of a 59 year old woman who presented with clinical features of localized bronchiectasis, who on detailed evaluation was found to have this rare tumour.

A dot-immunobinding assay (dot-Iba) for rapid diagnosis of pulmonary tuberculosis.

IgG antibody to Mycobacterium tuberculosis from the sera of patients with 'definite' pulmonary tuberculosis (PT) was isolated and coupled with Cyanogen bromide-Sepharose 4B. Using an immunoabsorbent affinity chromatography, 14 kDa antigen was recovered from the culture filtrates of M. tuberculosis. With this mycobacterial antigen, a dot immunobinding assay (Dot-Iba) was developed for the detection of specific antibody to M. tuberculosis in the sera of patients with PT and controls. The assay gave positive results in all the 12 sputum-smear positive [acid fast bacilli (AFB)] patients with PT and gave negative results in the 50 sera from control groups. The Dot-Iba as described in this study, is simple, rapid and specific for laboratory diagnosis of PT.