RESUMEN
Diabetes and thyroid diseases are two familiar endocrinopathies seen in the general population. Abnormal thyroid hormone levels can also be found in individuals with diabetes. Metformin may lower thyroid stimulating hormone levels both in hypothyroid as well as euthyroid individuals. To this purpose,we studied analys is of serum TSH levels in patients with type-2 DM who were receiving metformin and compared them with serum TSH levels of those individuals with T2DM that were not on metformin. Study participants were selected from the people residing in neighbouring vill ages in and adjoining Kadapa district of Andhra Pradesh. Study duration was 6 months between June-November 2008. Sample size was 80 subjects with T2DM on Metformin and 80 subjects with T2DM receiving non Metformin based therapy were included in the study.Data were entered in Microsoft Excel 2007 and data was expressed as mean and standard deviation (Mean±SD). Serum TSH values, metformin dose and metformin duration were not normally distributed. Comparison of difference in means between the two groups for normally distributed continuous variables namely age HbA1c, R.V. Rama Narayana Reddy, T.A.R.Raja,.Senthil,Priyadharshini. Evaluation of thyroid hormone dysfunction in type -2 diabetes patients on metformin therapy –A cross sectional study. IAIM,2016; 3(1):24-28.Page 25 serum T3 and T4 was done by unpaired student’s t test. P <0.05 was treated as significant.Metformin utilize was not associated with changes in serum thyroid stimulating hormone levels in euthyroid type-2 DM patients. The presence of acomparative group of type 2 diabetes individuals not receiving Metformin add to the analytical value of the study design.
RESUMEN
'Anesthesia is nothing, but airway management' or 'Anesthesia is nothing without airway management', perhaps both are true. Airway anatomy and physiology in infants and small children differs markedly from the adults, and so are the problems associated with it. We have to adopt protocols, methods and techniques, specifically for this population. This special article is an overview of the current trends with a special reference to the future perspective in infant and pediatric airway management