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1.
Journal of Rheumatic Diseases ; : 32-35, 2011.
Artículo en Coreano | WPRIM | ID: wpr-47175

RESUMEN

Paraneoplastic cancer polyarthritis is a very rare manifestation of musculoskeletal disorders associated with several solid and hematologic malignancies. We describe a 71-year-old woman who presented initially with an abrupt onset of rheumatoid arthritis-like symmetrical polyarthritis. The patient was diagnosed with pancreatic cancer with multiple hepatic metastases approximately six months later. Her symptoms of polyarthritis improved after the introduction of medication including non-steroidal anti-inflammatory drugs and disease modifying anti-rheumatic drugs. This case suggests that a hidden malignancy should always be considered in elderly patients, who present with an abrupt onset of symmetric polyarthritis for the first time in their life.


Asunto(s)
Anciano , Femenino , Humanos , Antirreumáticos , Artritis , Artritis Reumatoide , Neoplasias Hematológicas , Metástasis de la Neoplasia , Neoplasias Pancreáticas , Síndromes Paraneoplásicos
2.
Korean Circulation Journal ; : 558-564, 2010.
Artículo en Inglés | WPRIM | ID: wpr-59735

RESUMEN

BACKGROUND AND OBJECTIVES: Recently, the prognostic value of N-terminal brain natriuretic peptide (NT-proBNP) in acute coronary syndrome has been demonstrated in many studies. However, NT-proBNP levels are influenced by various factors such as sex, age, renal function, heart failure severity, and obesity. NT-proBNP concentrations tend to decrease with higher body mass index (BMI). The aim of this study was to examine the influence of obesity on NT-proBNP as a predictive prognostic factor in acute myocardial infarction (AMI) patients. SUBJECTS AND METHODS: Using data from the Korea Acute Myocardial Infarction Registry (January 2005 to September 2008), 2,736 AMI patients were included in this study. These patients were divided into men (n=1,972, 70%) and women (n=764, 30%), and were grouped according to their BMIs. Major adverse cardiac events (MACE) during 1 year clinical follow-up were evaluated. RESULTS: NT-proBNP was significantly higher in lower BMI (p<0.001). Mean NT-proBNP levels of each obesity group were 2,393+/-4,022 pg/mL in the lean group (n=875), 1,506+/-3,074 pg/mL in the overweight group (n=724) and 1,100+/-1,137 pg/mL in the obese group (n=1,137) (p<0.01). NT-proBNP was an independent prognostic factor of AMI in obese patients by multivariative analysis of independent risk factors of MACE (p=0.01). CONCLUSION: NT-proBNP is lower in obese AMI patients than in non-obese AMI patients, but NT-proBNP is still of independent prognostic value in obese AMI patients.


Asunto(s)
Femenino , Humanos , Masculino , Síndrome Coronario Agudo , Índice de Masa Corporal , Encéfalo , Estudios de Seguimiento , Insuficiencia Cardíaca , Corea (Geográfico) , Infarto del Miocardio , Péptido Natriurético Encefálico , Obesidad , Sobrepeso , Fragmentos de Péptidos , Factores de Riesgo
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