Combination Therapy with Endoscopic Removal and Ambisome for Rhinocerebral Aspergillosis Invading Frontal Lobe: Report of a Case / 대한이비인후과학회지

The rhinocerebral aspergillosis invading sinuses and CNS is known to be a fatal desease in immunocompromised patients. The management principle of rhinocerebral aspergillosis is often by extensive surgical removal through craniotomy combined with amphotericin B therapy, and endoscopic removal had not been reported until now. We report in this study a case of rhinocerebral aspergillosis invading the left frontal sinus and the left frontal lobe which were treated by the combination therapy of endoscopic removal and antifungal agents.

A Case of Osteoblastoma Arising from the Ethmoid Sinus / 대한이비인후과학회지

Osteoblastoma is a benign bone tumor which commonly occurs in the vertebral column and the long bone of extremities, although the paranasal sinus involvement is very rare. We are reporting a case of benign osteoblastoma of the ethmoid sinus extending maxillary sinus and nasal cavity in a 66-year-old man who presented with progressive exophthalmos and intractable epiphora. The tumor was successfully removed via extended medial maxillectomy through lateral rhinotomy approach. Histologic features showed the central zone of edematous vascular fibrous tissue with scattered trabeculae of osteoid surrounded by the outer layer of dense mature bone. A differential diagnosis is necessary for various kinds of fibro-osseous lesions such as osteoid osteoma, ossifying fibroma and fibrous dysplasia.