The Effect of Body Mass Index, Fat Percentage, and Fat-free Mass Index on Pulmonary Function Test: With Particular Reference to Parameters Derived from Forced Expiratory Volume Curve / 결핵

BACKGROUND: Sex specific cross sectional reference values for the lung function indices usually employ a linear model with a term for age and height. The purpose of this study was to determine the effects of the body mass index (BMI), the fat percentage of the body mass and the fat-free mass index (FFMI) on the forced expiratory volume curve. METHOD: Between January 2000 and December 2001, a total of 300 subjects, 150 men and 150 women (mean age : 45+/-13 years), with a normal lung function were enrolled in the study sample. This study measured the FEV1, FVC and FEF25-75% from the forced expiratory volume curve by a spirometer and the body composition by a bioelectrical impedance method in all subjects. Multiple regression analysis was used in order to examine the effects of the body composition on the parameters derived from the forced expiratory volume curve. RESULT: After adjusting for age, the BMI and Fat percentage improved the descriptions of the FVC (p<0.05, r2=0.491) and FEV1 (p<0.05, r2=0.654) in women. In contrast, the FFMI contributed significantly to the FVC (p<0.05, r2=0.432) and FEV1 (p<0.05, r2=0.567) in men. The FEF25-75% correlated with the fat percentage in women (p<0.05, r2=0.337). CONCLUSION: These results suggest that the BMI, the fat percentage and the FFMI are significant determinants of the forced expiratory volume curve. The pulmonary function test, when considering the BMI, the fat percentage and the FFMI, might be useful in clinical applications.

Evaluation of factors affecting sensory neural hearing loss / 예방의학회지

Reports on a potential relationship between sensory neural hearing loss(SNHL) and cardiovascular or hematologic factor show that the results are controversial. A detailed analysis of risk factors in the development of SNHL was carried out in 3,050 non-noise exposed healthy worker. The mean hearing threshold of both ears at 500, 1000, 2000, 4000, 8000Hz was measured and the effect of age, possible cardiovascular risk factor and hematologic factor (blood viscosity and hemostatic factors) on SNHL were evaluated. First, each of these were associated with loss of hearing sensitivity when univariately and multivariatively analysed. In a multiple regression model, age, sex, body mass index, WBC and total cholesterol level were independently associated with the mean of hearing sensitivity decrease at 4000 and 8000Hz. Second, study subjects were divided into two group (normal vs SNHL) and we compare the possible risk between both groups, and analysed univariate and multivariative logistic model. In a multiple logistic regression model, age, sex, body mass index, WBC and total cholesterol level, total protein, platelet were independently associated with SNHL. Our results show that we have some reliable indices of susceptibility to SNHL using cardiovascular measures or biochemical factor, but future, more extensive studies are required.

Differences in Clinical Laboratory Data between the Elderly and the Young Adults / 영남의대학술지

Due to the lowering of biological functions resulted from old age, the elderly is known to have many different clinical laboratory data compared with the young adults. But, in korea, such study is lacking. This research is to find the differences between the elderly and the young adults, and also to know the sexual differences, by comparing the outcomes of the clinical laboratory data. Along with that, it is to help clinical usage of the data in the future. The age of the elderly was between 60 and 83(average age 63.8), and that of the young controls was between 20 and 35. In both sexes, MCV, MCH, ESR, CRP,AST, ALT, gamma GTP, ALP, BUN, total cholesterol were significantly higher in the elderly than in the controls. And lymphocyte count(%), total bilirubin, direct bilirubin, total protein, albumin, T3 were significantly lower in the elderly than in the controls(P<0.05). Hemoglobin, Hct, platelet count, T4 were significantly lower only in the male elderly, and eosinophil count(%), creatinine were significantly higher only in the female elderly(P<0.05). HDLcholesterol was significantly higher only in the male elderly(P<0.01). There were no significant difference between two groups regarding WBCcount, segment neutrophil count(%), monocyte count(%), TSH. Many clinical laboratory data are different between the elderly and the young adults, and some clinical laboratory data also have sexual differences.

A study on Perception and attitudes of Examinees of Health Screening Center towards health Examination / 영남의대학술지

A survey was conducted to study perception and attitudes of examinees of, health screening center towards items, cost and procedures of health examination and degree of satisfaction with health examination, from March 2 to May 31, 1995. The study population was 468 examinees received health examination at Health Screening & Diagnosis Center of Yeungnam University Hospital. A questionnaire method was used to collect data. The followings are summaries of findings Examinees were predominantly male(77.4%) ; had college education(68.6%), and held white-collar workers (57.8%). Statistical significance of association between frequency of periodic health examination and other variables