A case of neonatal thyrotoxicosis detected by neonatal tachycardia / 대한주산의학회잡지

Neonatal hyperthyrodism is rare and mainly develops in neonates born to mothers with a history of Graves' disease. The incidence is estimated to be 1% in pregnancies associated with thyroid disease. Clinical manifestations include intrauterine growth retardation, goiter, irritability, facial flushing, tachycardia, and exophthalmos. Symptoms are mostly transient, lasting up to 12 weeks or more. We present one case of neonatal thyrotoxicosis detected by tachycardia in a neonate in whom maternal Graves' disease was initially unrecognized.

Depressive and Anxious Tendency and Behavioral Abnormalities of Children Suffering from Recurrent Headache / 대한소아신경학회지

PURPOSE: Headache is a common disorder in childhood and adolescence and frequently associated with emotional or psychological problems. In this study we studied behavioral and psychological characteristics of recurrent headache patients. METHODS: We evaluated 120 patients over 9 years old with headache who visited Kangnam Sacred Heart Hospital. 33 patients who didn't have headache were included in the control group. Diagnosis was confirmed according to ICHD-2 classification and KCBCL, TAIC, CDI, and SAIC were conducted in all participants. RESULTS: Male to female ratio was 0.7:1 in the study group and 1.1:1 in the control group and the mean age was 11.5+/-2.1 and 12.6+/-2.0 years old respectively. 73.3% of patients were migraine and 26.7% were tension type headache. The mean of KCBCL total scores was 56.2 in the migraine group, 54.0 in the tension type headache group, and 38.3 in the control group and the score was higher in the headache group(P<0.001). The means of internalizing and externalizing scores were 59.8 and 54.1 in the migraine group, 57.4 and 51.3 in the tension headache group, and 40.1 and 42.4 in the control group respectively and the scores were higher in the headache group(P<0.001). The mean scores of SAIC and TAIC were 36.3 and 33.6 in the migraine group, 36.3 and 34.6 in the tension type headache group, and 25.3 and 26.9 in the control group respectively and the scores were higher in the headache group(P<0.001). The mean scores of CDI were 14.9 in the migraine group, 14.5 in the tension type headache group, and 9.1 in the control group and the scores were higher in the headache group(P=0.002). CONCLUSION: The patients with recurrent headache showed statistically significant higher scores in CBCL total, internalizing, and externalizing scores, SAIC, TAIC, and CDI in comparison with the control group.

The Effects of Family History on the Diagnosis of Childhood Migraine / 대한소아신경학회지

PURPOSE: Headache is a common problem in children and adolescents, and they experience severe pain and disabilities from headache. But there had not been an appropriate system for the diagnosis and the classification for headache in children and adolescents before the international classification of headache disorders(ICHD-II) was developed. But family history was not included in this classification's criteria. So we evaluated the effects of family history on the diagnosis of children with recurrent headaches. METHODS: 217 patients with recurrent headaches younger than fifteen years old were selected. To diagnose the patients' headache, we utilized headache questionnaires, headache diaries, and studied the family history of headache on the patients' maternal and paternal lines. Final diagnosis was based on the ICHD-II. RESULTS: In the migrainous patients, 78.1% had positive family history of headache on the maternal lines, and 16.2% on the paternal lines. In the patients with tension-type headache, 56.8% had positive family history of headache on the maternal lines. When the mother of a patient suffered from recurrent headaches, migraine occurred 2.94 times as frequently as tension-type headache(Mantel-Haenszel odds ratio, 2.94; P<0.01; 95% confidence interval, 1.36-6.38). And if a patient had parents with recurrent headaches, migraine occurred 3.22 times as frequently as tension-type headache(odds ratio, 3.22; P<0.005; 95% confidence interval, 1.48-7.02). CONCLUSION: We can consider migraine rather than tension-type headache when a patient has family history of recurrent headaches. In our study, we were able to validate that positive family history of headache was important in diagnosing the headache of children.