RESUMEN
Background: Cardiac rehabilitation is a branch of rehabilitation medicine dealing with optimizing physical function in patients with atherosclerosis after coronary artery bypass graft [CABG]. The aim of this study was to investigate the effects of a period of cardiac rehabilitation on serum levels of apo-A1 and apo-B in middle aged men with myocardial infarction after CABG
Materials and methods: Subjects were selected among middle aged men [50 to 60 years old] with CABG and assigned into two groups of control [n=10] and experimental [n=10]. In experimental group, aerobic exercises [treadmill, cycle and hand ergometer] with the intensity of 11 to 13 on the [basis of burg scale] were performed during eight weeks under control of physician. Before and after the trainings, serum levels of ApoA1 and ApoB were measured by ELISA method
Results: Analysis of data using paired samples T test showed no changes in weight, BMI, levels of apo-A1 and apo-B and apo-B to apo-A1 ratio in control group [P>0.05], but in experimental group weight, BMI, apo-B and apo-B to apo-A1 ratio significantly decreased and apo-A1 increased [P<0.05]. On the basis of independent T-test results, changes of weight, BMI and ApoA1 were significantly differed between two groups [P<0.05]
Conclusion: Eight weeks cardiac rehabilitation, through reduction of apo-A1 and apo-B, can be effective in prevention of recurrent myocardial infarction and morbidity and mortality in middle aged men after CABG