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1.
Indian J Pathol Microbiol ; 2011 Jan-Mar 54(1): 3-6
Artículo en Inglés | IMSEAR | ID: sea-141882

RESUMEN

Background: Immunoglobulin M nephropathy (IgMN) is an idiopathic glomerulonephritis (GN) usually presenting clinically as steroid resistant/dependent nephrotic syndrome (NS) with pathology of mesangial proliferative GN or focal and segmental glomerulosclerosis with diffuse predominant mesangial IgM deposits. Not much information is available about its natural history. This is the first Indian study to our knowledge on IgMN in adults and adolescents. Materials and Methods: We evaluated renal biopsies performed at our center between January,'04 to September,'09. Biopsies of all adolescents and adults were evaluated for IgMN and we studied their age, gender distribution, blood pressure (BP), disease duration, steroid/immunosuppressive management and serial serum creatinine (SCr), urinary proteins, and BP values. Patients with other systemic diseases/infections and children were excluded. Results: IgMN constituted 4.3% of 2702 adult renal biopsies. No significant gender predilection was noted. Males presented at average age of 23.1 years, females at 30 years. Steroid-dependent NS was the commonest presentation noted in 75% followed by steroid-resistant NS. Hypertension was noted in 10% patients. Mesangial proliferative GN (MePGN) was commonest histopathological finding noted in 74.4%, followed by focal segmental glomerulosclerosis (FSGS) in 16.2%, and minimal change disease (MCD) in 9.4% biopsies. Sole IgM deposits were noted in 88.5%. All MCD, 35.6% MePGN reached remission, FSGS progressed to renal failure by 1 year. Hypertension, proteinuria, interstitial fibrosis, and FSGS were bad prognosticators. Conclusions: This is the first Indian study of IgMN in adults and adolescents carried out over a period of 5.8 years, which has shown that hypertension, proteinuria, and interstitial fibrosis at presentation have bad prognosis.


Asunto(s)
Adolescente , Adulto , Anciano , Biopsia , Femenino , Glomerulonefritis/inducido químicamente , Glomerulonefritis/epidemiología , Humanos , Inmunoglobulina M/toxicidad , India/epidemiología , Riñón/patología , Masculino , Persona de Mediana Edad , Prevalencia , Factores de Riesgo , Adulto Joven
3.
Indian J Med Microbiol ; 2003 Jul-Sep; 21(3): 207-8
Artículo en Inglés | IMSEAR | ID: sea-53557

RESUMEN

This paper describes a case of pleural effusion due to filariasis. Microfilaria of Wucheraria bancrofti were detected in the pleural fluid on cytological examination. Treatment with diethylcarbamazine cleared the pleural effusion.

5.
Indian J Pediatr ; 1992 Jul-Aug; 59(4): 435-42
Artículo en Inglés | IMSEAR | ID: sea-83117

RESUMEN

Five hundred children below the age of 12 years suffering from lung tuberculosis viz., primary complex (PC) or progressive primary complex (PPC) were studied. Diagnosis was based on Kenneth Jones criteria; selected cases having score of 5 or more. One hundred and eighty cases of PC were given A-1 (6 RH) regimen, while 312 cases of PPC were given A-2 (2SHRZ/4 RH) or A-3 (2 SRH/4 RH) or A-4 (2 RHE/4 RH) regimen. Follow-up was done for 6 months after completing the treatment to observe the relapse rate. In cases of PC, 6 RH regimen appeared adequate and cheaper with no relapse rate. In cases of PPC with short course chemotherapy, compliance of patients had been very good. Relapse rate was up to 13% which is acceptable. Drug toxicity was very low.


Asunto(s)
Antituberculosos/uso terapéutico , Niño , Preescolar , Estudios Transversales , Países en Desarrollo , Esquema de Medicación , Quimioterapia Combinada , Femenino , Humanos , Incidencia , India/epidemiología , Lactante , Masculino , Tuberculosis Pulmonar/diagnóstico
7.
Indian Pediatr ; 1982 Aug; 19(8): 695-9
Artículo en Inglés | IMSEAR | ID: sea-9813
8.
J Indian Med Assoc ; 1980 May; 74(10): 187-8
Artículo en Inglés | IMSEAR | ID: sea-100717
9.
Indian J Med Sci ; 1974 Feb; 28(2): 89-93
Artículo en Inglés | IMSEAR | ID: sea-68552
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