Seroprevalence Of Hepatitis B Virus In Patients Admitted To Era’S Lucknow Medical College And Hospital

Hepatitis-B Virus infections are a serious global and public health problem. To assess the magnitude and dynamics of disease transmission and for its prevention and control, the study of its seroprevalence is important. A medical college catering to the needs of a large population represents an important centre for serological surveys. Available data, on the seroprevalence of these bloodborne pathogens is also very limited. A study was undertaken to estimate the seroprevalence of Hepatitis-B Surface Antigen (HBsAg) in both the sexes and different age groups in a hospital-based population. Serum samples collected over a period of 24 months from patients admitted to various IPDs of Era’s Lucknow Medical College and Hospital, Lucknow were subjected within the hospital-based microbiology lab for the detection of HBsAg using ELISA test. The seroprevalence of HBsAg was found to be 1.92%. The study throws light on the magnitude of viral transmission in the community in Lucknow city and provides a reference for future studies.

Carcinoma oesophagus in a 14 year old child: report of a case and review of literature.

A 14 year old boy with well differentiated squamous cell carcinoma of the upper oesophagus is being presented because of its rarity. The patient presented with dysphagia for 8 months. Barium swallow and endoscopy revealed a narrowing in the upper oesophagus with a proximal dilatation diverticulum. No definite aetiologic factor could be demonstrated. The case was treated with definitive irradiation with excellent immediate response.

Electron beam irradiation in treatment of skin carcinoma.

Thirty seven cases of carcinoma of skin treated with electron-beam irradiation over a period of three years have been analysed retrospectively. Majority of lesions were in head and neck and basal-cell carcinoma was the commonest histological type. Of twenty-one patients followed, seventeen (81%) achieved complete remission and remained disease free for a period of one to three years. Cosmetic results were excellent. Role of electron-beam in the management of these superficial cancers and its advantage over the conventional radiation therapy methods have been highlighted. Radiation therapy utilising electron-beams form a very useful modality in the management of skin cancers, especially those arising in head and neck.