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To explore the treatment effects of HydroCoil Embolic System [HES] on large- and med sized intracranial aneurysms. Fifty cases of intracranial aneurysm patients were retrospectively analyzed, in which 27 an cases were treated with HES [n=27] and ordinary coils [n=23], respectively. All the patients were followed up for two years. The 27 cases [54%, 27/50] treated with HES include 23 cases of densely packed occlusion [23/50] and 4 cases of subtotal occlusion [8%, 4/50]. The 23 cases [46%, 23/50] treated with ordinary include 15 cases of densely packed occlusion [30%, 15/50] and 8 cases of subtotal occlusion [16%, 8/5. HydroCoil Embolic System [HES] may increase the ratio of densely packed occlusion prevent the recurrence of large- and medium-sized intracranial aneurysms
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Objective To explore the relationship between chemokine receptor CXCR4 expression and invasiveness of pituitary adenomas. Methods A total of 78 pituitary adenoma specimens with comprehensive clinical data were surgically removed in Southwest hospital and 5 normal pituitary tissue samples were used as control. All the samples were fixed with 10 % formalin and then embedded with paraffin. Every case history was reviewed in detail. All the specimens were divided into invasive group (35 cases) and non-invasive group (43 cases) by the combined application of Knosp imaging diagnosis standard and Renzuyuan’s standard and referring to all operation records. The expressions of CXCR4 protein in 83 specimens were examined by immunohistochemistry. The relation between the expression of CXCR4 protein and invasiveness of the pituitary adenomas was analyzed. Results Immunohistochemistry showed that there was significantly high CXCR4 protein expression in invasive group and low in non-invasive group and normal pituitary tissue. There was a significant correlation between the expression level of CXCR4 protein and invasiveness of the pituitary adenomas (P005). Conclusion High CXCR4 protein expression is associated with the invasiveness of pituitary adenomas, suggesting that the expression of CXCR4 may have a value to assess the invasive pituitary adenomas.
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Contrasted with the conventional sterilization, the one by gas plasma, has many advantages, especially for the disinfection of heat-sensitive materials. The paper mainly introduced the characteristics and the application fields of plasma sterilization, the mechanism of plasma sterilization, the researches at home and abroad in recent years and the factors which effected the efficiency of sterilization. The problems in the plasma sterilization were discussed and the future research works in this field were also put forward.