RESUMEN
Apesar da atividade farmacológica de Mikania glomerata Spreng. ser conhecida desde longa data, existem poucos estudos visando a preparação de produtos padronizados que garantam uma produção uniforme, doses eficazes e estabilidade. Nesse trabalho, foram realizados ensaios objetivando a otimização do processo extrativo; tratamento da droga vegetal para o preparo de tinturas; determinação da melhor forma de estocagem e otimização da preparação da forma farmacêutica (xarope).
Although the pharmacological activity of Mikania glomerata Spreng. has been well known for a long time, there are a few studies concerning the elaboration of phytopharmaceutical products that assure an uniform preparation, effective doses and stability. In this work, tests with the objective of the optimization of the extraction process were performed; treatment of the plant drug for preparation of tinctures; determination of the adequate form of storage and the optimization of the preparation of the pharmaceutical form (syrup).
RESUMEN
Medicinal plants still account for 25 per cent of medical prescriptions in developed countries and for more than 80 per cent in developing countries. Vegetable raw materials available in the commercial market frequently do not comply with the requirements of constant activity, efficacy and quality. There is a need for more strict specifications of vegetable drugs and the pharmacopoeial prescriptions usually provide these specifications. The characteristics of pharmacopoeial prescriptions are discussed in view of most common problems in drug qaulity.