RESUMEN
OBJECTIVES: This study was done to determine the infectious association of congenital cataract based on presence of antibodies against TORCH [Toxoplasma gondii, Rubella virus, Cytomegalovirus and Herpes simplex virus] in the serum sample of congenital cataract patients
METHODS: Serum Samples collected from 68 infants [10 days to 1 year] with clinically diagnosed Congenital Cataract at Department of Ophthalmology Unit-I, Dow Medical College and Civil Hospital, Karachi from June 2011 to January 2013
RESULTS: Antibodies against TORCH organisms were present in 16 [23.52%] patients. 10[14.7%] out of them were males and 6 [8.82%] were female. 11 [16.17%] patients had antibodies against one infectious agent and 5 [7.35%] patients had antibodies against two or more infectiousagents
CONCLUSION: Majority of Patients with positive antibodies were positive for Cytomegalovirus
Antibodies against Rubella and Herpes Simplex Virus were less commonly associated in this patient population. None positive for Toxoplasma gondii
RESUMEN
OBJECTIVE: To determine the efficiency of probing in partial nasolacrimal duct obstruction [NLD] in adults
STUDY DESIGN: Prospective study
PLACE AND DURATION OF STUDY: Department of Ophthalmology unit 1, Dow University of Health Sciences, Civil Hospital Karachi from January 2006 to July 2011
METHODOLOGY: This study includes 340 patients complaining of watering of the eye for more than 6 months duration from partial NLD obstruction. Eye examination was done to exclude other causes of watering. ENT opinion was taken to exclude nasal pathology. Risk and benefits of probing were explained to all patients and their written consent was taken. Probing was done in operation theatre under aseptic conditions in local anaesthesia. Probe was left in place for 02 minutes to allow dilatation of nasolacrimal duct. Post probing, patients were given topical antibiotics for 1 week and were followed for a period of 06 months
RESULTS: Out of 340 patients only 35 [10.3%] patients became asymptomatic, rest of the patient came back with epiphora within 02 months
CONCLUSION: Probing of NLD in adults for partial obstrution gives symptomatic relief only in a few cases and majority of patients need surgical intervention