Chemical constituents from whole plants of Valeriana hardwickii / 中国中药杂志

Chemical investigation of the whole plants of Valeriana hardwickii has led to the isolation of 11 flavones and 2 monoterpe- noids by using various chromatographic techniques including column chromatography on silica gel and Sephadex LH-20, preparative TLC, and preparative HPLC. Their structures were identified by spectroscopic data analysis as syzalterin (1), 6-methylapigenin (2), 5-hydroxy-7,4'-dimethoxyflavone (3), genkwanin (4), acacetin (5), apigenin (6), quercetin (7), tricin (8), (-)-farrerol (9), sosakuranetin (10), 5,3',4'-trihydroxy-7-methoxyflavanone (11), (-)-bornyl ferulate ( 12) , and (-)-bornyl caffeate ( 13). All compounds were isolated from this plant for the first time, while compounds 1, 9-13 were obtained from this genus for the first time.

Traditional Chinese medicine injection clinical use management model for evaluation / 中国中药杂志

<p><b>OBJECTIVE</b>Discussion on assessment and intervention models to promote the rational use of medicines of Chinese medicine injection effect.</p><p><b>METHOD</b>Using systematic prescription assessment and intervention work mode, formed expert group guide established assessment standard, developed the prescription audit specification, and extracted all Chinese medicine injection prescription of outpatient 2010 first quarter (in front of intervention) and 2011 first quarter (behind intervention), respectively for 2 543 and 3 122.</p><p><b>RESULT</b>The percent of the non-indication of medication in front of intervention outpatient fell from 3.44% to behind intervention of 2.66% (P<0.05), the percent of contraindicated medication in front of intervention outpatient fell from 2. 14% to behind intervention of 1.33% (P<0.05), the incidence of adverse reactions in front of intervention outpatient fell from 1.01% to behind intervention of 0.29% (P<0.05).</p><p><b>CONCLUSION</b>The modes of prescription assessment and intervention have obvious results for the promotion of rational use of traditional Chinese medicine injections.</p>