new concept in the treatment of periapical lesions using honey

Thirty periapical lesions were divided into two similar groups. In the first group, the lesions were irrigated via the root canal with 70% diluted pure honey for three successive times every 48 hours. In the second group, normal saline was used for this purpose. Surgical removal of the lesions for histopathological examination were made at 2, 4, 6, 8, and 12 weeks following the last irrigation in both groups. The results revealed that the honey treated lesions exhibited marked and rapid healing than the normal saline treated lesions. This finding encourages the use of honey in the treatment of periapical leions and open a way for using honey in other oral surgical procedures