Chemical constituents of ethyl acetate fraction from the stems of Saprosma merrillii Lo / 中国药学杂志

OBJECTIVE: To study the chemical constituents of the ethyl acetate fraction from the stems of Saprosma merrillii Lo. METHODS: The compounds were isolated and purified by silica gel column and Sephadex LH-20 column. Their structures were elucidated on the basis of chemical properties and spectral analysis. RESULTS: Ten compounds were isolated and elucidated as 5-hydroxylmethylfuraldehyde(1), 3β-hydroxycholesta-5-ene (2), scopoletin(3), isoscopoletin(4), quercetin-3-O-glucoside-6"-gallate (5), 4'-hydroxy-7-methoxy flavanone(6), pinoresinol (7), N-trans-coumaroyltyramine (8), luteolin-7-O-B-G-glucopyranoside(9), and hypodiolide A(10). CONCLUSION: All of the compounds are isolated from this genus for the first time except for compound 3.