RESUMEN
Background: Epidural anesthesia is the most commonly usedtechnique for inducing surgical anesthesia and postoperativeanalgesia in lower abdominal and limb surgeries.Dexmedetomidine is a highly selective α2-adrenergic agonistwhich has been used for premedication and as an adjunct togeneral anaesthesia. Hence; the present study was undertakenfor assessing the effects of dexmedetomidine used as anadjuvant in epidural post-operative analgesia.Materials and Methods: A total of 30 female patientsscheduled to undergo total abdominal hysterectomies wereenrolled for the study. Complete demographic and clinicalprofile of all the patients was obtained. Clinical examination ofall the patients was carried out and a 10 cm visual analog scale(VAS) (0, no pain and 10, worst pain imaginable) was used forassessing patient pain score. A combined spinal and epiduraltechnique was used for anesthesia and postoperativeanalgesia. Shifting of the patient to the recovery room wasdone after completion of the surgery. The first dose of epiduraldose was given when VAS score was equal to or more than 3.All patients received a total volume of 10 ml of levobupivacaine0.125% with dexmedetomidine 1 μg/kg. All the results wereanalyzed by SPSS software.Results: Mean duration of surgery in the present study was98.5 minutes. Mean duration of analgesia was found to be389.4 minutes. Mean time for onset of analgesia was found tobe 6.95 minutes. In 12 cases, rescue analgesia was required.Conclusion: Dexmedetomidine might be used as an Adjuvantin Epidural Post-Operative Analgesia.
RESUMEN
Background: Women undergoing procedures or surgeriesrelated to infertility experience pain, which is often treated withopioid medication. Hence; the present study was undertakenfor assessing analgesic efficacy of the non- opioid analgesic inpatients following abdominal hysterectomy at a tertiary carecenter.Materials and Methods: A total of 30 patients scheduled toundergo abdominal hysterectomy were enrolled in the presentstudy. All the patients underwent abdominal hysterectomyunder the hands of skilled clinicians. All the patients weredivided broadly into three study groups: Group 1: Patients weregiven placebo Group 2: Patients were given metamizol 1 g,and Group 3: Patients were given paracetamol 1 g. The drugswere dissolved in 100 mL normal saline and given via IVinfusion over 15 minutes. Patients in the placebo groupreceived only 100 mL of normal saline. All the postoperativedata in all the patients was recorded. All the results wereanalyzed by SPSS software.Results: In the present study, a total of 30 patients wereanalyzed. Mean age of the patients of the study group 1, 2 and3 was 42.8 years, 40.1 years and 43.8 years respective. MeanBMI of the patients of the study group, 2 and 3 was 27, 25.9and 26.1 Kg/m2respectively. In the present study, whilecomparing the Frequency of Patient controlled analgesia bolusdemands among the four study groups, non-significant resultswere obtained.Conclusion: Both metamizol and paracetamol can be usedwith equal efficacy in patients following abdominalhysterectomy.