Prevalence of Non-albicans Candida and its Antifungal Susceptibility at a Tertiary Care Hospital, Jaipur

Introduction: Acute appendicitis is one of the most commonsurgical emergencies. Accurate diagnosis of acute appendicitisneeds careful history, and physical evaluation, as the diagnosisis primarily clinical.Material and methods: A cross sectional study was done in50 patients who underwent emergency appendicectomy foracute appendicitis in a medical college hospital in Shimla.The aim was to study the clinical profile of patients with acuteappendicitis and compare it with the existing literature.Results: Mean age of patients was 26.48 (± 12.28) years.Out of 50 patients, 29 (58%) were males and 21 (42%) werefemales, so male predominance was seen in the present study.Most common complaints were pain in the right iliac fossa(100%), nausea and vomiting (82%), anorexia (80%), andmigration of pain (70%). Tenderness in right iliac fossa waspresent in all patients in our study (100%), while reboundtenderness (70%), guarding (64%), rigidity (6%), Rovsingsign (36%), Psoas sign (46%), Obturator sign (22%), andDunphy sign (60%), respectively.Conclusions: Acute appendicitis is more common amongmales than females, and between 10- 30 yrs of age. Themost common presenting features were pain abdomen,anorexia, nausea, and vomiting. The most common signs weretenderness, rebound tenderness and guarding. The rate ofaccuracy of clinical examination was 86%

The Correlation of Spurious Eosinophilia in Automated Hematological Analyzer Sysmex Xs-800i with Plasmodium Infection Diagnosis.

Context: Automated analyzers based on flow cytometry have evolved as an effective adjuvant diagnostic tool in malaria diagnosis. Aim: To find out the correlation of interpretive (IP) message from automated hematology analyzer XS-800i and Plasmodium infection diagnosed in peripheral smear. Settings and Design: Prospective study carried over a period of 2 years (July 2010 to June 2012). Materials and Methods: All cases with IP message of eosinophilia in Sysmex XS-800i analyzer were screened for microscopic correlation of eosinophilia and other peripheral smear findings. Results: In 24 out of 5012 patients with eosinophilia, microscopic eosinophil counts were normal. In these 24 cases, IP message in hematology analyzers was that the eosinophilia and WBC scattergram showed narrowed space between the eosinophil and neutrophil population. On careful examination of the peripheral smears of all 5012 cases, 39 cases revealed different stages of Plasmodium vivax (trophozoites, schizonts or gametocytes) in erythrocytes. Conclusion: Peripheral smears of the cases having inconsistent eosinophilia result with that of Sysmex XS-800i analyzer should be examined carefully for the presence of malaria parasites in the red blood cells. Sysmex XS-800i analyzers have moderate range of sensitivity and high degree of specificity in diagnosing malaria as spurious eosinophilia.