1.
Chinese Journal of Clinical Pharmacology and Therapeutics
; (12): 316-327, 2024.
Artículo
en Chino
| WPRIM
| ID: wpr-1014543
RESUMEN
Positron emission tomography (PET) now plays an important role in the research and development (R&D) of central nervous system (CNS) drugs. PET could characterize the biodistribution, pharmacokinetics, and receptor binding of CNS drugs quantitatively. The present review summarized the quantitative methods of PET used in the pharmacokinetics and receptor occupancy analysis of CNS drugs. Moreover, the present review listed various applications of PET supporting R&D of CNS drugs, which could provide a new direction for the R&D of CNS drugs.