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Professional Medical Journal-Quarterly [The]. 2012; 19 (5): 683-687
en Inglés | IMEMR | ID: emr-151326

RESUMEN

The present work was undertaken to analyze qualitatively the serum electrolyte [K[+], Na[+], Mg[2+], PO4[-3] and Cl[-]] levels by photometric analysis in cancer patients as compared to non-cancer individuals. An understanding of the mechanisms involved in disease pathogenesis is paramount for prevention and treatment in cancer patients. Total 120 blood samples were collected for analysis randomly which were divided into two groups as A [leukemia patients] and B [normal individuals] having 60 in each. Both of these groups were further sub-divided [20 each] into three age groups [20-35, 36-50 and 51-70] A1, B1, A2, B2, A3, B3 respectively. A significant [p<0.05] increase in serum K[+] level [hyperkalemia] was observed in cancer patients as compared to normal individuals having a non significant [P>0.05] interaction with the age limits. However a significant decrease [P<0.05] in the levels of Mg[2+], PO4[-3] and Cl[-] [hypomagnesia, h pophosphatemia and hypochloridemia respectively] was recorded in group B as compared to group A having independency of age limits. Low serum Na[+] [hyponatremia] was observed in Group B3 as compared to Group A3 [51-70] except the age limits [20-35 and 36- 50] which showed a non significant interaction with this decreased level of sodium. The data was statistically analyzed by ANOVA and a highly significant [P< 0.05] difference was obtained between both of the groups

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