Prevalence of nosocomial infection in Thailand 2006.

OBJECTIVE: To study the prevalence of nosocomial infection (NI). MATERIAL AND METHOD: A point prevalence study was done in 20 hospitals across the country in August 2006. RESULTS: The present study was done in 20 hospitals: three university, five regional, five provincial, and seven other hospitals. 9,865 patients were included Male and female patients were almost equal in number with an average age of 42.7 years. The NI proportion was 6.5%, 7.0% in male and 5.9% in female patients. The prevalence rate of NI was highest in university and other hospitals (7.6%), followed by provincial (6.0%), and regional hospital (4.9%). There were two hospitals, one regional and one other hospital with NI prevalence rates over 10%. All three university hospitals had NI exceeding 7%. The infection rate was highest in ICU (22.6%), followed by surgical (6.8%), medical and orthopedic (6.7% each) departments. The commonest site of NI was lower respiratory tract (36.1%) followed by urinary tract (25.5%). Causative organisms were identified in 70.8% of all sites of infection and over 63% were by bacteria. Gram-negative bacteria were responsible for 70.2% and gram-positive bacteria for 19.9% of all pathogens. Pseudomonas aeruginosa, Klebsiella spp., Acinetobacter baumannii, MRSA, and enterococci were the leading bacterial isolates. At the time of the present study, 47.0% of patients were receiving antimicrobials. Cephalosporins, penicillins, and aminoglycosides were most commonly used CONCLUSION: The prevalence rate of NI in Thailand in 2006 was 6.5%, similar to previous studies. Changes in NI rates in certain hospitals, even though subtle, need additional studies to improve the efficacy of NI control.

A study for the production of containers used in the diagnosis and prevention of infection.

OBJECTIVES: 1. To study the need of containers used in the diagnosis and prevention of infection. 2. To produce the containers, 3. To test the practicability of the product. MATERIAL AND METHOD: - The study on the need of the containers was done by questionnaires answered by nurses and microbiology laboratory technicians in 56 hospitals. - The containers were produced by the researchers who later had them tested for their practicability by nurses and technicians in the same hospitals. - The study was done during 2002-2004. RESULTS: Fifty-six hospitals were enrolled by stratified random sampling. Questionnaires were responded by 424 nurses and 35 microbiology laboratory technicians. Sputum trap, body fluid and feces containers and needle disposal box were studied and the need for commercial products was 31.1%, 31.1%, 32.3% and 99.5% respectively. Sixteen percent to 58.5% of these containers were bought and 14.3% to 68.6% were home-made. Sputum trap, body fluid and feces containers, and needle disposal boxes were produced and tested by 400 nurses and 32 laboratory technicians. The products were evaluated as satisfactory in 59.4% to 80.0%. The lid of the needle disposal box designed as saw tooth was not convenient for use and was later modified to various slits. The costs of the containers produced were 1.3% to 29.8% of available commercial products. CONCLUSION: Sputum trap, body fluid and feces containers and needle disposal boxes of reasonable prices were needed in Thailand. These containers could be produced locally and were much cheaper than available commercial ones.

Bacterial flora--A potential source of endophthalmitis after cataract surgery.

OBJECTIVES: To study bacteria from eye lids and conjunctival sac of patients undergoing cataract surgery before and after the application of antiseptics. MATERIAL AND METHOD: Patients undergoing elective cataract extraction in one university hospital were randomly enrolled. Cultures for bacteria and candida were done by swabbing the eye lids before and after cleaning with 4% chlorhexidine gluconate. Subsequently 10% povidone iodine was applied on eye lids and conjunctival sacs. Cultures of specimens from eye lids and conjunctival sac were taken after the application of 10% povidone iodine and at the end of the operation. RESULTS: Fifty-one patients were enrolled. Positive cultures were found in 90.2% and 82.4% before and after cleaning the face with 4% chlorhexidine. After topical application of 10% povidone iodine, only 19.6% had positive cultures from eye lids and conjunctival sac; a significant reduction (p=0.001). At the end of the operation, positive cultures were found from eye lids in 10 patients and from the conjunctival sac in 4 patients. Isolates were skin flora and candida species in 2 patients. None of the patients had endophthalmitis. CONCLUSION: Cleaning eye lids with 4% chlorhexidine followed by applying 10% povidone iodine was effective in decreasing skin flora in cataract surgery. The organisms were not completely eliminated. Postoperative follow-up to detect infectious complications is warranted.

Program on nosocomial infection in the curricula of medicine, dentistry, nursing and medical technology in Thailand.

OBJECTIVES: To identify defects in the program on NI in curricula of medical, dental, medical technology and nursing schools. Impacts of the results of the study on the changes of the program were also evaluated MATERIAL AND METHOD: Questionnaires study of all 12, 8, 9 medical, dental, medical technology and 20 of 62 nursing schools. Data were collected and analyzed. Defects in the program of NI were identified and recommendation for improving was drafted in a workshop participated by curriculum directors and researchers. Results of the study were fedback to the schools enrolled. Changes of the program were later followed.. RESULTS: Program on NI was present in the curricula of 11 of 12 medical, some dental and medical technology but in none of the nursing schools. Education program varied in methods of teaching, hours and years of students. A few schools modified the program in their curricula by the results of the study and recommendation of a workshop participated in by researchers and program directors. CONCLUSION: Program on NI in the curricula of medical, dental, medical technology and nursing schools in Thailand varied in education methods, teaching hours and in student years. The present study results had little impact on changing the program. An evidence-based program on NI in medical, dentistry, medical technology and nursing is urgently needed.