Clinicostatistical Study of Malignant Tumors in Infants and Children

Clinicostatistical study was carried out on 130 cases of children with malignant tumors admitted in pediatric ward of Severance Hospital from 1965 to 1974 and the following results were obtained: 1) The incidence of malignancies on all admitted cases was 1.0% and males were more affected(68.5%) than females. 2) The annual increase of incidence on childhood malignancies couldn't be observed. 3) The highest incidence of malignancies (50.0%) was noted in preschool age group of children (1~6 Yrs). 4) The most common malignancy was leukemia (59.1%) and tumors arising from neural origin were next common. 5) The common sites of organ involvement by malignancies were RES including blood (77 cases), brain (17 cases) and sympathetic nerve (14 cases) in order of incidence. 6) The tentative diagnosis of malignancy was made on 80.8% of all cases at the time of admission. 7) Anemia and bleeding tendency were main problems in leukemic children (40 casse) on admission and mass or abdominal distension in the children with neuroblastoma, lymphoma and hepatoma. 8) Mean admission days of children with malignancy were 2 weeks and 20% of all cases were died in the hospital. 28.5% of all cases were improved at the time of discharge and 19.2% wree discharged against advice.

Clinical Studies on Congenital Heart Disease (1964~1975)

The clinical studies were performed on 757 patients who had been admitted to Severance Hospital from May, 1964 to June, 1975 with the diagnosis of congenital heart disease. The following results were obtained; 1. Among 757 patients, cardiac catheterization was performed on 367 patients. 2. Four hundred and thirty eight patients were male and 319 were female. Over half of them were below two years of age, but among 357 cardiac catheterized patients, 137 (37.3%) patients were ranged between 6 to 10 years. 3. V.S.D., Tetralogy of Fallot, P.D.A., A.S.D. were found in order of frequency. 4. Among 757 patients, combined extra-cardiac anomalies were found in 42 patients, and 14 patients were with Downanjx syndrome. 5. Among 367 cardiac catheterized patients, 164 (44.7%) patients had cardiac operations, and among these, 18 (11.0%) patients died including 7 patients of Tetralogy of Fallot.