RESUMEN
Objectives@#Youths can function as agents of change by disseminating essential information, but they are also considered a vulnerable group in the COVID-19 pandemic. Literature on COVID-related knowledge, attitude, and anxiety has not focused comprehensively on youths. This study assesses the knowledge, attitudes, and anxiety level of youths in eastern Nigeria during the COVID-19 pandemic.@*Methods@#We conducted a descriptive cross-sectional study using an online survey among young people between the ages of 18 and 35 years in southeastern Nigeria during the COVID-19 pandemic. We analyzed data using the Statistical Package for Social Science (SPSS) version 25 software. We used descriptive statistics, the Chi-square test, and bivariate and multivariate logistic regression analyses to measure the associations. A p-value of < 0.05 was considered statistically significant at a 95 percent confidence level.@*Results@#We included 397 participants. Majority of the study participants (88%) had a high level of knowledge about COVID-19. Around 68% showed a good attitude toward COVID-19 prevention, overall low anxiety related to the COVID-19 pandemic was proportionally higher at 57.43%. Knowledge and educational level were statistically significantly associated with anxiety levels related to the COVID-19 pandemic. @*Conclusion@#The young adults had a good knowledge of the COVID-19 transmission and symptoms, positive attitude, and low anxiety levels. Those with higher educational levels had good knowledge and lower anxiety level. Public health and mental health experts can use this material to help reduce high levels of anxiety among the vulnerable population affected by the pandemic.