Spectrum of Histopathological Findings in Liver Biopsy.

The significance of abnormal liver function tests in the absence of diagnostic serology is unclear. The aim of this prospective study is to report liver biopsy findings in a large group of patients with unexplained abnormal liver biochemistry and correlate them with the clinical features to assess the severity of these diseases. Percutaneous liver biopsy is a relatively safe and accurate method of diagnosing liver disease and should be considered in such cases. A total of 65 liver biopsies were studied, of which, 26.15% (n=17) hepatic tumors, 23.08% (n=15) cirrhosis, 20.00% (n=13) fatty liver and 06.15% (n=4) viral hepatitis were seen. Further, 01.54% case (n=1) each of alcoholic hepatitis, benign recurrent intrahepatic cholestasis, extrahepatic biliary atresia, granulomatous hepatitis, neonatal hepatitis, Niemann-Pick disease and secondary biliary cirrhosis were also observed. Liver biopsy was non specific in 9.23% (n=6) and inadequate in 4.62% (n=3) cases .The role of histopathological examination of liver biopsy is highlighted in this paper.

Visceral leishmaniasis in the Dhofar region of Oman

The clinical presentation, frequency distribution of symptoms and signs and laboratory findings were studied in the suspected cases of kala azar admitted to the paediatric wards of sultan Qaboos Hospital, salalah, during period February 1992 to april 1994. response to therapy with sodium stibogluconate was excellent. Mortality in these cases were not encountered

unusual case of acute flaccid paralysis

Rhabdomyolysis leading to acute flaccid paralysis in a one-year old girl is reported. She developed respiratory failure needing ventilatory assistance eventually making a complete recovery