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Southeast Asian J Trop Med Public Health ; 1993 Mar; 24(1): 126-9
Artículo en Inglés | IMSEAR | ID: sea-30597

RESUMEN

Pasteur cholera vaccine consists of isolated antigenic fractions from V. cholerae El Tor Ogawa and Inaba. Enteric coated microgranules were prepared from antigen lyophilisate. Three doses of this vaccine were administered orally to 19 healthy young Thai adults at one week intervals. None of the volunteers experienced untowards reactions. The vibriocidal antibody responses manifested a significant antibody rise (> or = 4 fold) to serovar Inaba in 8 vaccinees (42.1%) and Ogawa in 4 (21.1%). Five and 6 vaccinees (26.3% and 31.6%) showed a > or = 4 fold rise of IgG and IgA anti-LPS, respectively.


Asunto(s)
Administración Oral , Adulto , Anticuerpos Antibacterianos/inmunología , Vacunas contra el Cólera/administración & dosificación , Femenino , Humanos , Masculino , Vibrio cholerae/inmunología
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