RESUMEN
To compare the efficacy of antenatal synergistic muscles facilitation on pelvic floor versus kegels exercises on postpartum pelvic floor muscle strength. Quasi-experimental, Post-test only design with a comparison group. Department of Obstetrics and Gynecology, P. S. Govindasamy Hospitals, Coimbatore, Tamilnadu, India. Seventy-eight antenatal women were randomly selected. Among the 78 women, 39 each were assigned to Group A [interventional group] and to Group B [control group]. Finally 21 women in each group continued the treatment program. o Group A- synergistic muscles of pelvic floor [Diaphragm, Abdominals, Ankle dorsiflexors and pelvic floor muscles] o Group B - kegels exercises [Only pelvic floor muscles]. The pelvic floor muscle strength was measured using Perineometer after 30 days. Data from 42 women were analyzed. Independent t- test was used as statistical tool. A significant difference in the postpartum pelvic floor muscle strength was found between the interventional and the control group. The mean difference between the interventional and control group was 1.762mm hg. The calculated t value using independent t- test was 3.584 which was greater than tabulated test statistical value of the 1.960 at [p < 0.05]. The pelvic floor muscle strength was comparatively greater among the women who performed synergistic muscle re-education than kegels exercise group. Hence, antenatal Motor Relearning approach of diaphragmatic, deep abdominal and pelvic floor exercises can be implemented during a normal pregnancy unless precluded by additional risk factors
RESUMEN
Ethanol extract and its ethanol fraction from aerial parts of P. daemia exhibited significant hepatoprotective effect against CCl4 induced hepatotoxicity in rats. Glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, alkaline phosphatase, total bilirubin, total cholesterol, total protein and albumin in serum indicated hepatoprotective effect of the ethanol extract and its ethanol fraction. Histopathological examination of liver sections confirmed that, pre-treatment with ethanol extract and its ethanol fraction prevented hepatic damage induced by CCl4. The results were comparable with the standard hepatoprotective drug silymarin. The extract and its fraction showed no signs of toxicity up to a dose level of 2000 mg/kg. It is suggested that, the presence of flavonoids in ethanol extract and its ethanol fraction may be responsible for hepatoprotective properties. High Performance Thin Layer Chromatography profile of flavonoids of bio-active extracts was developed using quercetin-3-glucoside as a marker. Results indicate hepatoprotective properties of ethanol extract of P. daemia.