RESUMEN
The MeOH extract of P. Pinnata [leaves] decreased the ulcer index significantly. A significant decrease in volume of gastic Juice, acid output and peptic activity was recorded. A decrease in protein concentration and increase in total carbohydrates had led to an increase in mucin activity in acetylsalicylic acid [ASA] ulcerated rats, however, peptic activity and mucin activity remained unchanged in normal pylorus ligated rats. The result of the present study tend to confirm that MeOH extract of P. pinnata strengthens mucosal resistance and promotes the healing of the ulcers. The MeOH extract of N. sativa has shown a decrease in volume of gastric juice secreted and peptic activity in ASA ulcerated rats. A qualitative change in carbohydrates concents was found in ASA treated rats, however, mucin activity remained unchanged. A significant change in mucin activity was however, found in normal pylorus ligated rats treated with MeOH extracts of N. sativa